Si Nuo. : 1303-28-2
Chinese name: arsenic pentoxide
English name: arsenic oxide; ; Arsenic anhydride
Nickname: arsenic anhydride
Molecular formula: As2O5 appearance and properties: white amorphous solid, easily deliquescent.
Molecular weight: 229.84 vapor pressure
Melting point: 3 15℃ (decomposed), soluble in water, soluble in ethanol, acid and alkali.
Density: Relative density (air = 1)4.32 is stable.
Danger sign: 13 (inorganic drama drugs)
Main uses: used to prepare drugs, pesticides, metal welding agents and non-ferrous metal glass.
I. Health hazards
Invasion route: inhalation, ingestion and percutaneous absorption.
Health hazard: Arsenic and its compounds have special affinity for the sulfur group of enzyme proteins in vivo.
Acute poisoning: acute gastroenteritis, shock, peripheral neuropathy, anemia, toxic liver disease and myocarditis caused by oral administration. Will die of respiratory center paralysis. Inhalation in a large amount in a short time can cause cough, chest pain, dyspnea, headache, dizziness and so on. The symptoms of digestive tract are mild, and other symptoms seem to be taken orally. In severe cases, it can be fatal.
Chronic effects: Chronic poisoning caused by long-term exposure to high-concentration dust mainly includes neurasthenia syndrome, polyneuropathy, liver injury, rhinitis, perforation of nasal septum and bronchitis.
Second, toxic information and environmental behavior
Toxicity: extremely toxic.
Acute toxicity: LD508mg/kg (taken orally by rats); 55mg/kg (taken orally by mice).
Mutagenicity: DNA repair: Bacillus subtilis 50 mmol/L. Cytogenetic analysis: human cells1200 nm0l/L.
Reproductive toxicity: The lowest toxic dose (TDL 0) of subcutaneous injection in mice: 4597 μ g/kg (30 days, male), affecting testis and vas deferens.
Carcinogenicity: IARC carcinogenicity review: artificially positive; Animals are not clear.
Hazard characteristics: In case of high heat and open flame, it will produce highly toxic steam.
Combustion (decomposition) product: arsenic oxide.
Chemical formula: As2O3
GBNo。 6 1007
Si Nuo. 1327-53-3
arsenic trioxide
English name As2O3; ; Arsenic anhydride
Also known as arsenic, anhydrous arsenic acid, arsenic, arsenic.
Molecular weight 197.84
Properties: There are three states: amorphous, equiaxed, monoclinic or colorless powder. They are easily reduced and oxidized.
Melting point: arsenite 275℃, white arsenite 3 13℃
Boiling point 457.2℃
Steam pressure 13.33 kPa (332.5 degrees Celsius)
Solubility slightly soluble in water (solubility: 2g/ 100ml), soluble in acid and alkali.
Density Relative density (water = 1)3.86
Stability stability
Danger sign 13 (inorganic drama drugs)
Mainly used in glass, enamel, pigment industry and pesticides, leather preservatives and so on.
Amorphous glassy substance (glassy arsenic) in amorphous system. Unstable, it can gradually become an equiaxed crystal system.
Arsenite is a small crystal (powder) with white equiaxed octahedron. It is most stable even at room temperature. It sublimates at 135℃ and transforms into monoclinic system at 22 1℃.
Claudetite is a colorless needle-like crystal with monoclinic system, which is stable above 2265438 0℃.
Toxicity: extremely toxic.
Acute toxicity: LD5020mg/kg (taken orally by rats); 45 mg/kg (taken orally by mice).
Irritation: rabbit eyes: 50ug(24 hours), severe irritation. Percutaneous rabbit: 5mg(24 hours), severely irritating.
Subacute and chronic toxicity: Rats ingested150mg (kg day) for ***6.5 months, which had a slight effect on the growth and development of animals; The weight of liver and kidney increased obviously, but the function of liver and kidney and blood routine were normal. Below 30mg/kg, the main organs of animals have no pathological changes.
Mutagenicity: DNA inhibits human Hela cells at 500 umol/L Cytogenetic analysis: human leukocyte1200 nmol/L.
Reproductive toxicity: The lowest toxic concentration (TCL 0) of mice is 28500 ug/m3(4 hours, 9 ~ 12 days pregnant), which causes cytological changes and normal musculoskeletal development.
Carcinogenicity: IARC carcinogenicity review: human positive; Animals are not clear.
Hazard characteristics: Highly toxic gas will be produced when exposed to high heat and sublimation.
Combustion (decomposition) product: arsenic oxide.