Can regular contact with molybdenum do harm to the body? Come on, everybody, 3Q.

Both human and animal bodies have a strong internal stability mechanism for molybdenum, and oral intake of molybdenum compounds is not easy to cause poisoning. It is reported that the daily molybdenum intake of residents living in Armenia is as high as10 ~15 mg; The high incidence of local gout is thought to be related to this. Workers in molybdenum smelters can also take in too much molybdenum by inhaling molybdenum-containing dust. According to the investigation, the serum molybdenum level, xanthine oxidase activity and uric acid level in blood and urine of these workers are significantly higher than those of the general population. Metabolize and absorb molybdenum compounds in diet and drinking water, which is easy to absorb. About 88%-93% of oral soluble ammonium molybdate can be absorbed. Various sulfur-containing compounds in the diet have a strong inhibitory effect on the absorption of molybdenum, and molybdenum sulfide can only absorb about 5% after oral administration. After being absorbed, molybdate still binds to macroglobulin in blood in the form of molybdate, and loosely binds to red blood cells. Most of the molybdenum in the blood is absorbed by the liver and kidney. Part of molybdate in liver is converted into molybdenum-containing enzyme, and the rest is combined with pterin to form molybdenum-containing auxiliary group, which is stored in liver. The body excretes molybdenum mainly through the kidney in the form of molybdate. With the increase of dietary molybdenum intake, the amount of molybdenum excreted by the kidney also increases. Therefore, the human body mainly maintains the balance of molybdenum in the body through renal excretion rather than through controlled absorption. In addition, a certain amount of molybdenum is excreted with bile. Physiological Function Molybdenum plays its physiological function as the auxiliary group of three molybdenum metalloenzymes. Molybdenum enzyme catalyzes the hydroxylation of some substrates. Xanthine oxidase catalyzes the conversion of hypoxanthine into xanthine and then into uric acid. Aldehyde oxidase catalyzes the oxidation and detoxification of various pyrimidine, purine, pteridine and related compounds. Sulfite oxidase catalyzes the conversion of sulfite into sulfate. Some researchers have also found that molybdate can protect adrenocortical hormone receptors and keep them active in vitro. It is speculated that it may have a similar effect in the body. It is speculated that molybdate can affect glucocorticoid receptor because it is an endogenous compound called "regulator" Physiological needs In 2000, China Nutrition Society formulated the reference dietary molybdenum intake of China residents according to foreign data, and the suitable intake for adults was 60ug/d; The maximum tolerable intake is 350 ug/d silvery white metal, which is hard and tough. The density is10.2g/cm3. The melting point is 26 10℃. The boiling point is 5560℃. The valence is +2, +4, +6, and the stable price is +6. Molybdenum is a transition element, which can easily change its oxidation state and play the role of transferring electrons in redox reactions in vivo. In the oxidized form, molybdenum may be in the valence state of +6. Although it is likely to be reduced to +5 valence state first in the process of electron transfer, other oxidation states of molybdenum peroxide are also found in the reduced enzyme. Molybdenum is a component of xanthine oxidase/dehydrogenase, aldehyde oxidase and sulfite oxidase, so it is known to be an essential trace element for human body, animals and plants. Molybdenum is contained in various tissues of human body, and the total amount in adults is 9mg, with the highest content in liver and kidney. Pure molybdenum wire is used in high temperature electric furnace, EDM and WEDM. Molybdenum sheets are used to make wireless electrical villages and X-ray equipment; Adding molybdenum to alloy steel can improve the elastic limit, resist corrosion and maintain permanent magnetism. Molybdenum is one of the seven trace elements needed for plant growth and development. Without it, plants can't survive. Animals and fish need molybdenum as much as plants.