When you take the first sip of wine, alcohol will directly enter your blood through the gastric mucosa and spread throughout the body along the blood vessels. The stomach absorbs alcohol much faster than the small intestine absorbs water. The blood vessels in the whole body immediately begin to dilate and the blood circulation is accelerated, which is why many people feel warm after drinking, and your heart rate is also accelerating. Only 10% alcohol is excreted through sweat and respiration, and the rest needs to be metabolized by your liver. The liver first decomposes ethanol into acetaldehyde through ethanol dehydrogenase; Then acetaldehyde is decomposed into acetic acid by acetaldehyde dehydrogenase. Acetic acid will not cause harm to the body, but acetaldehyde will quickly follow the cell membrane destroyed by alcohol and easily enter the cell interior. Destroy the genes in the nucleus, leaving a permanent hidden danger? Canceration.
You may say that acetaldehyde is converted into acetic acid very quickly, and there is no chance to cause harm to human body, but in fact, Japanese research shows that about 40% of Japanese people have mutant acetaldehyde dehydrogenase 2 gene, which is similar to that of China people. In other words, as an East Asian, you have at least a 40% chance that acetaldehyde dehydrogenase is under-secreted, which leads to abnormal alcohol metabolism and a large amount of acetaldehyde remains in your body. Not only that, alcohol can also do harm to your stomach, intestines, brain and heart? Do it. Vomiting and dizziness are only external manifestations, but in fact they will cause brain atrophy, decrease the number of white blood cells in the body, myocardial prolapse and liver sclerosis and hypertrophy.
Maybe many people still don't believe that a little wine is harmful to health. If you drink a small amount of alcohol, isn't the alcohol dehydrogenase produced by your body enough to decompose acetaldehyde into acetic acid? The Lancet, an authoritative medical journal, published a study on August 23rd, 20 18, which involved 27 years' drinking risk analysis of 28 million drinkers in 195 countries and regions. The study found that there was no alcohol at all? Safe dose? . Compared with people who don't drink at all, people who drink a glass of wine every day (10g alcohol, equivalent to a can of beer, 100ml red wine or 30ml white wine) have an increased risk of health problems by 0.5%. When the daily alcohol consumption rose to 2 cups and 5 cups respectively, this figure rose rapidly to 7% and 37% respectively.
Some patients with coronary heart disease will drink a little wine every day to soften blood vessels. In fact, an article published in the Journal of American Heart Association in 20 16 showed that after two years of research, it was found that the risk of atrial fibrillation caused by regular so-called small drinking increased by 8%, and the risk of drinking one more glass a day increased by 8%. For people with angina pectoris, alcohol intake should be strictly controlled. Patients with angina pectoris often use nitro anti-angina drugs during the attack. Nitro-antianginal drugs can affect alcohol metabolism, which not only makes acetaldehyde easy to stay, but also causes diseases. But also lead to a small amount of drinking, and may also lead to drunkenness. It is easy to induce angina pectoris to recur or worsen after drunkenness. Therefore, patients with angina pectoris who may use anti-angina drugs at any time should not drink alcohol. However, people who blush after drinking alcohol are actually defective in acetaldehyde dehydrogenase 2 gene, which is more likely to cause acetaldehyde to stay in the body and cause esophageal cancer.
For diabetic patients, alcohol will hinder the liver from generating glycogen, and when combined with hypoglycemic drugs, it will cause severe hypoglycemia. Severe hypoglycemia is sometimes confused with drunkenness, which is often mistaken for drunkenness and delayed treatment, which is likely to lead to hypoglycemia death. For patients with hypertension, alcohol can raise blood pressure. This is very dangerous for patients with hypertension, which can easily lead to cardiovascular and cerebrovascular diseases such as vascular rupture, sudden stroke, aortic dissection and arrhythmia. In addition, it is best for patients not to drink alcohol during taking medicine, especially during taking cephalosporins. The superposition of the two will cause disulfiram reaction and lead to death. Danger may occur within 7 days after drug withdrawal. It seems that moderate drinking can keep health, which is just everyone's good wish, because drinking, even if it is only a drop, will do harm to the body. Therefore, compared with people who drink a little wine every day, teetotalers are healthier.