Can patients with thyroid diseases take minocycline hydrochloride capsules to have side effects?

Minocycline hydrochloride capsules are semi-synthetic tetracycline broad-spectrum antibiotics with high efficiency and long-acting effect. Among tetracycline antibiotics, this product has the strongest antibacterial effect. The antibacterial spectrum is similar to tetracycline. It has a strong effect on gram-positive bacteria including tetracycline-resistant Staphylococcus aureus and Streptococcus, and gonorrhea-resistant bacteria among gram-negative bacteria. The effect on gram-negative bacilli is generally weak; This product also has a good inhibitory effect on chlamydia trachomatis and ureaplasma urealyticum. In recent years, due to the abuse of tetracycline antibiotics, most common gram-positive bacteria and gram-negative bacteria have developed resistance to minocycline hydrochloride capsules. The mechanism of action of this product is to bind with the A position of ribosome 30S subunit, and prevent the extension of peptide chain, thus inhibiting the protein synthesis of bacteria or other pathogenic microorganisms. This product is an antibacterial drug, but it also has bactericidal effect at high concentration. Toxicological minocycline hydrochloride capsules can cause the thyroid gland of experimental animals (rats, dogs and monkeys) to turn black. Rats were given this product for chronic treatment, resulting in goiter and even thyroid tumor. This product can also cause thyroid hyperplasia in rats and dogs. Long-term use of minocycline hydrochloride capsules can make the thyroid turn brown-black, and abnormal thyroid function is rare. In fact, no matter what kind of medicine, eating too much will have certain side effects. Therefore, minocycline hydrochloride capsules should not be taken in excess. Also, minocycline hydrochloride capsules should be taken under the guidance of a doctor, and strict attention should be paid to drug hygiene. In this way, minocycline hydrochloride capsules will not produce some adverse reactions. I hope it helps you!