Is that really the case? Moderate drinking won't hurt the liver?
After wine enters the human body, most of the alcohol will be absorbed by the gastrointestinal tract of the human body and blended into the blood. Then it is responsible for "detoxification" with the blood entering the liver. Enzymes secreted by the liver will react with alcohol to decompose alcohol into acetaldehyde, and then turn acetaldehyde into acetic acid. When acetic acid decomposes again, it becomes water and carbon dioxide. Then it will be metabolized and excreted by the human body.
When a large amount of alcohol enters the human body, the liver can't decompose all the alcohol in a short time.
In this process, a large amount of alcohol that has been metabolized into acetaldehyde will first combine with protein in human body, and then it can be decomposed into acetic acid to form acetaldehyde-protein complex, which can directly damage the liver. This is the reason why drinking hurts the liver.
In other words, drinking alcohol can damage the liver, mainly because alcohol is at work. In other words, as long as you drink alcohol, alcohol will cause damage to the human liver. The higher the alcohol content, the greater the damage to the human liver.
In addition, drinking will cause other harm to human body, even moderate drinking will cause other harm to human body.
According to the research report published in The Lancet magazine, for every four units of alcohol consumed every day, the probability of stroke of drinkers increases by an average of one third, and even a small amount of alcohol will do harm to human body. In the report, the recommended alcohol consumption is 0, and drinking is not recommended.
20 19 The research of China Academy of Medical Sciences shows that even a small amount of drinking will increase the risk of hypertension and stroke, especially ischemic stroke and cerebral hemorrhage, which is highly related to alcohol. The more you drink, the higher the risk of inducing these diseases.
Above, we said that drinking alcohol hurts the liver, but there is also a risk of cancer.
Research by the International Agency for Research on Cancer (IARC) shows that the occurrence of cancer is closely related to alcohol. Studies have shown that about a quarter of cancers are related to alcohol, which is an important factor leading to cancer. Especially breast cancer and colorectal cancer, people who drink alcohol for a long time are more likely to induce these two malignant diseases.
At the same time, IARC pointed out that from the geographical distribution, East Asia, Central Europe and Eastern Europe are high-risk areas for alcohol carcinogenesis.
According to a study published in The Lancet, drinking alcohol will increase the burden of cancer in the world, especially in East Asia, led by China people.
Researchers say that in 2020, about 740,000 new cancer cases around the world are highly related to alcohol. Among them, East Asia is the most seriously affected, including China and Mongolia, and cancer cases caused by drinking account for the highest proportion of the total number of new cases.
According to the research report published in the journal Nature, people with acetaldehyde dehydrogenase gene deficiency are more vulnerable to alcohol injury. This common genetic variation exists in many people's genes in China, which will greatly reduce people's tolerance to alcohol.
At the same time, most people in China still carry another gene, that is "Dukang gene".
Dukang gene is a variant of plasma antidiuretic hormone. Many people in China carry this gene, and about 70% of the Han people have this gene. Plasma antidiuretic hormone can promote the production of acetaldehyde, but acetaldehyde related to alcohol was listed as a carcinogen by the World Health Organization as early as 20 17.
People with "Du Kang" gene will secrete more plasma antidiuretic hormone and metabolize ethanol faster.
However, people with acetaldehyde dehydrogenase gene deficiency have insufficient ability to effectively degrade acetaldehyde, and the decomposed acetaldehyde cannot be quickly decomposed into acetic acid, so it will remain in the human body, causing greater harm to the human body.
On the one hand, there are a lot of decomposed acetaldehyde, on the other hand, these acetaldehyde are difficult to be decomposed again. These acetaldehyde will destroy human health like a scourge.
In other words, because of these two genes, some people in China are more likely to get cancer if they drink alcohol.
1, blushing after drinking
Earlier, we said that people with acetaldehyde dehydrogenase gene deficiency are more likely to cause liver damage due to drinking. One notable feature of this group of people is that they blush when drinking. The risk of liver cancer induced by long-term drinking in this group of people is also much higher than that of the general population.
Therefore, it is recommended that this group of people, it is best not to drink.
2, the face is yellow
If you have the habit of drinking, you will find that your face is different from mine. Your face is dull and yellow, so pay attention. Maybe your liver is damaged.
After drinking heavily for a long time, if a person's liver is damaged and his liver function declines, he can't metabolize toxins quickly. Toxins will be deposited in the body, and the skin on the human surface will change over time, becoming dull, dull, yellow and rough.
If this happens, you should immediately stop drinking and quit drinking habits to avoid further damage to the liver and induce alcoholic fatty liver or cirrhosis.
3. Abdominal pain
Many people will feel stomachache after drinking, so pay special attention at this time.
Abdominal pain after drinking may be caused by drinking, such as gastric bleeding, liver cancer, acute pancreatitis, gastric ulcer and so on.
If abdominal pain lasts for a long time, it is recommended to go to the hospital immediately to prevent certain diseases.
If you have ever had abdominal pain after drinking, and it is obvious, it means that our body may have some kind of disease because of alcohol disease. Advise such people to give up drinking.
1, pregnant women and children
Alcohol can cause extremely serious harm to pregnant women and fetuses. Alcohol has a strong permeability. Although the fetus has placental protection, it can block many viruses and harmful substances in food. However, placenta can not effectively prevent alcohol from harming the fetus.
Excessive drinking in pregnant women may lead to fetal abortion, increase the probability of inducing various diseases, increase the risk of fetal malformation, and may also damage the fetal nervous system.
However, children are still in the development stage, and their physical functions are relatively fragile, and the damage of drinking to their organs will be higher than that of adults. In addition, children who drink alcohol are more likely to induce liver diseases such as fatty liver and cirrhosis than those who don't drink alcohol.
Alcohol can damage the central nervous system of human body, and excessive drinking can cause dizziness, dizziness, headache and memory loss. If the alcohol content in the human body is relatively high, it may also inhibit people's breathing, and long-term drinking will make people physically dependent on alcohol. Therefore, children are not advised to drink alcohol, nor are they advised to drink any alcoholic beverages.
2. Patients with liver disease
The liver of patients with liver disease has been damaged, and if they drink alcohol again, it will inevitably lead to more serious liver damage. In fact, a small amount of drinking may also increase liver enzymes (transaminase) in the human body. Alcohol may also be related to liver diseases.
It is found that the combination of alcohol and hepatitis B virus may increase the spread and proliferation of chronic inflammation and accelerate the development of hepatitis B, and drinking by hepatitis B virus carriers will also accelerate the development of hepatitis B virus into viral hepatitis. Drinking alcohol may cause patients with viral hepatitis to develop liver cancer at an early stage.
In addition, because alcohol is an important factor to induce fatty liver, long-term drinking may increase the accumulated fat in patients with fatty liver, which may increase the probability of fatty liver disease developing into cirrhosis.
Excessive drinking may also lead to excessive secretion of pancreatic juice in the human body for a short time, and patients with liver disease may have incomplete metabolism and stay in the pancreas, which may also lead to acute pancreatitis. Once acute pancreatitis is induced, pancreatic juice can destroy human pancreas and surrounding organs in a short time. It can cause multiple organ failure and other malignant reactions in a short time, such as heart failure, gastrorrhagia and renal failure. , even life-threatening.
Therefore, patients with liver disease are not advised to drink alcohol, and moderate drinking is not acceptable.
In addition, patients with kidney disease, hypertension, heart disease and pancreatitis are not advised to drink alcohol.
Long-term drinking may not only increase the probability of inducing fatty liver, but also directly induce alcoholic fatty liver. In addition, alcohol will aggravate the pathological changes of liver disease, aggravate the condition of patients with viral hepatitis, and even induce liver cancer.
Moreover, long-term drinking is not only harmful to the liver, but also an important factor in inducing many diseases, such as heart disease, stroke, atherosclerosis, hypertension, coronary heart disease and other cardiovascular and cerebrovascular diseases. It can also induce diseases such as pancreatitis, gastrorrhagia and renal failure.
So in daily life, it is best not to drink alcohol.