For normal healthy people, bone marrow extraction is not too harmful and has no sequelae. Only when the bone marrow is extracted will there be such tearing pains. Generally speaking, it will recover in a few hours. For special people, extracting bone marrow is harmful, such as blood coagulation disorder and hemophilia. Because of these two reasons, patients have poor coagulation function. After bone marrow extraction, there will be local non-coagulation, continuous bleeding, resulting in massive bleeding and wound needle non-healing, with serious consequences. Another situation is that the patient's own immunity is low, which is seen in diseases or low immunity caused by drugs. This kind of patients recover very slowly when receiving bone marrow puncture, which is easy to cause weakness and even secondary infection and other complications. Therefore, a perfect examination should be carried out before bone marrow extraction to reduce the harm to the person who extracts bone marrow.