Research by the Anti-Aging Center shows that aging generally begins at around 25 years old and accelerates with age. Aging begins with cells. When the function of cells gradually declines or loses to a certain extent, it will lead to the decline or loss of the functions of various organs of the human body, which will lead to aging. Cell activity is poor, regeneration ability is weak, death is fast, and aging is accelerated.
Under normal circumstances, human cells are bound to die. According to scientists, cells will "age" after dividing 50~ 10 times. But what is the reason for getting old?
The harm of aging factor mda
Modern medicine has proved that the "culprit" of aging is free radicals-atoms or molecules with asymmetric electrons that are constantly produced in the process of human metabolism. Free radicals invade human cells to produce aging factor mda, and MDA further invades cells to produce lipofuscin, which is deposited in human cells, causing cell damage.
Lipfuscin is deposited in the cells of various tissues and organs of human body, which leads to the slow metabolism and decreased activity of cells, thus leading to the decline of human organ function and aging. Human cells synthesize anti-aging enzyme "gsh-px", whose main function is to scavenge free radicals, but with the increase of age, its synthetic ability and activity decrease. Aging factors gradually increased, and the content and activity of anti-aging enzymes decreased, so aging was born!
● Lipoprotein is deposited in immune organs, and the body's immunity is reduced;
● lipofuscin is deposited in brain cells, which leads to memory loss, confusion of thinking and decreased sleep quality;
● lipofuscin is deposited in skin cells, which makes the skin rough, dull and dull, and wrinkles and spots appear;
● lipofuscin is deposited in lens cells, and degeneration leads to visual impairment;
● When lipofuscin is deposited in hair, white hair or even hair loss will occur;
When lipofuscin is deposited in fat cells, it will promote fat accumulation;
● When lipofuscin is deposited on the blood vessel wall, atherosclerosis will be formed.
Lipfuscin is deposited in blood, which will do harm to cardiovascular and cerebrovascular health;
Lipoprotein is deposited in hepatocytes, which will affect the health of the liver and make it unable to function regularly;
Low lipofuscin deposition will also reduce the body's secretion of estrogen and androgen.
Related links: Common manifestations of aging
The common manifestations of aging are as follows.
1. Unexplained fatigue and fatigue cannot be completely relieved after proper rest;
2. It is easy to get tired and the quality of life declines;
3, emotional instability, excitability, bad temper or depression, irritability;
4. The skin loses elasticity and dullness, and various spots, wrinkles, bags under the eyes and dark circles appear, with excessive dandruff, white hair falling off easily, and abnormal nail surface and color;
5, the brain is confused, slow to respond, memory is obviously reduced, vision is reduced, and dizziness;
6, look bad, glassy-eyed, listless, often dizzy, stuffy head, tinnitus, deafness;
7. Poor diet, frequent indigestion, constipation and loose stool;
8. Limb weakness, backache, stiff neck and shoulders, increased abdominal fat, obesity or emaciation;
9. Unexplained fever or chills, sweating and night sweats, facial flushing, cold hands and feet;
10, often insomnia, sleep is not deep, dreamy, stay in bed.
People always hope to delay aging and prolong life. Despite repeated efforts, the average life expectancy of human beings has only increased from 45 years old more than 2,000 years ago to 74 years old. Up to now, the longest life span of human beings is only that of Englishman Bk Frem? Kahn lived for 200 years. Scientists point out that the natural life span of human beings should be 100- 150 years. At present, the actual life span of human beings is obviously far from this.
Why do people age? Can you suppress aging? This is one of the hot topics that scientists are most interested in at present. At present, the scientific and technological circles have studied the problem of human aging from different angles and put forward their own opinions. Who is who needs further confirmation from scientists.
Some scientists believe that human beings will accumulate harmful free radicals due to radiation exposure, taking chemicals, excessive iron content in food and other factors. This free radical is the chief culprit leading to human aging. Biochemical physicists at the University of Louisville in the United States extracted a substance that can eliminate free radicals in animals and used it to feed mosquitoes, thus prolonging the average life span of 1200 mosquitoes from 29 days to 45 days. Accordingly, if this substance can be injected into the human body to eliminate free radicals in the body, people's life can be prolonged.
Some scientists believe that cell aging is due to the production of some substances that cause aging. Cell Biology of Rockefeller University >>
Question 2: What is unnatural death? What is natural death? Accidental death is unnatural death.
Abnormal death in forensic medicine refers to death caused by external effects, including natural disasters such as fire and drowning; Or industrial injury, medical accident, traffic accident, suicide, murder, injury, etc. In contrast, normal death refers to death caused by internal health reasons, such as illness or old age. Abnormal death refers to some accidental casualties, which are caused by abnormal laws and can only be determined after forensic examination; Unexplained death is first classified as abnormal death, and may be reclassified as normal death (such as myocardial infarction) after the cause of death is determined. Abnormal death can only be determined by forensic examination. General provisions of local public security organs: If there is a suspected abnormal death, the relevant departments shall conduct inspection to find out the cause of death. If the relatives of the deceased have objections to the inspection results, they shall re-examine them afterwards. In addition, if family members request to keep the remains, they should be allowed to keep them for a period of time after approval. Natural death refers to the death that conforms to the natural development law of life and disease without violent intervention. Divided into aging death and disease death. Legal natural death, also known as physical death, refers to the end of a natural person's life. Brain death is the loss of whole brain function. Brain death has no function of brain stem and medulla oblongata except the loss of brain function, so after artificial respiration and circulation, the respiratory system and cardiovascular system cannot operate. All kinds of reactions do not exist, and there is no response to the outside world. Empty skull sign (even if artificial circulation is maintained, there is no flowing blood in intracranial vessels), and there is no EEG activity. The diagnosis of brain death does have a limit of 48 hours, but it refers to 48 hours after the brain electrical activity stops.
Question 3: What are the causes of natural death? Assuming that a human individual has no major genetic defects, adequate food, and no pathogens that he can't be immunized in the environment, then with the passage of time, the cells of this human individual will occasionally make mistakes when they are constantly replicating themselves, and gene replication errors will lead to the decline of cell skills or even the complete loss of some functions, and continue to replicate, and errors will continue to accumulate. Even without cancer cells, the destroyed cells will continue to replicate themselves. After several rounds of cell replacement, most of the cells in this individual are defective cells, and all the functions of the body will be greatly reduced. This goes on and on until one day, because the heart cells are too old to activate blood, or the brain cells are too old to maintain operation, or the kidneys are too old to dialyze blood, or the muscles responsible for swallowing muscles atrophy and cannot eat, and so on, the individual dies.
Question 4: What organ aging is the cause of natural death?
Question 5: Why do people die of natural causes? People will die naturally, because the number of cell divisions and the life span of human cells are limited.
Human cells are the structural and functional units of the human body. * * * There are about 400,000 -60 trillion cells with an average diameter of 10-20 microns. In the whole human body, 1 100 million cells die every minute. The life span of intestinal mucosal cells is 3 days, that of liver cells is 500 days, and that of nerve cells in brain and bone marrow is several decades, almost equivalent to that of human body. Some white blood cells in the blood can only live for a few hours.
The theory of cell algebra (also known as the theory of cell division times) holds that human cells are equivalent to a new generation every 2.4 years. Experiments show that human cells can be cultured for an average of 50 generations under culture conditions, each generation is equivalent to 2.4 years, which is called the Friec coefficient. Accordingly, the average life expectancy of people should be 2.4×50= 120 years old.
Question 6: There is only one cause of natural death? Natural death is a legal declaration of death. As far as death is concerned, death is divided into natural death and declared death. As long as it is not a natural person who has been missing for more than three years, it is a natural death if an interested person requests the court to declare death, such as illness or being killed.
Question 7: Why do people die of natural aging? Every cell has its own life span. With the apoptosis of cells, human beings will age slowly. This will be learned in biology class in high school.
Question 8: The old man died of natural causes. Does the death certificate require a cause of death? There are two kinds of natural death certificates, 100. First, if a person dies after being treated by a medical and health unit, the medical certificate of death shall be used. Second, if a citizen dies normally and cannot obtain a death certificate issued by the hospital, the certificate issued by the neighborhood (village) Committee does not need to be stated.