China International Experts Exchange Network Lin Jidong
Gynostemma pentaphyllum is a twisted plant of Cucurbitaceae. This kind of grass that has grown in the mountains for thousands of years is a weed that people look down upon. Although it has been used in folk for more than 1000 years. It is mainly used for diminishing inflammation, detoxicating, relieving cough and eliminating phlegm. Now it is mostly used as a tonic. It has not attracted enough attention in the medical field. There was basically no such medicine in Chinese medicine shops until 1976, when Japanese scientists successfully extracted Gynostemma pentaphyllum saponin, the main component of Gynostemma pentaphyllum, and made a lot of research on its pharmacological effects. In the past twenty years, scientists all over the world have been discussing the effects of studying this plant. In 1990s, American scientists conducted extensive research on Gynostemma pentaphyllum, and found that every plant in its family contains different components. Since the 1980s, we first discovered the fine variety of this plant-wild Gynostemma pentaphyllum, and then discovered Gynostemma pentaphyllum. After years of research, we found that Gynostemma pentaphyllum has four categories: three leaves, five leaves, seven leaves and nine leaves, and each category has its own advantages and disadvantages. The medicinal and health functions of each species are very different, so Trifolium and Pentaphyllum are classified as inferior varieties. The lowest content of gypenosides is only 65,438+0.5%-65,438+0.3%, with cold nature and bitter taste. Seven leaves each contain 3% of bitter and sweet taste, 4%-7% of sweet taste and 8%-65,438+02% of nine leaves. Gynostemma pentaphyllum has extensive special effects on human body. Seven leaves and nine leaves are also bitter. Its function is much stronger than that of Gynostemma pentaphyllum with three leaves and five leaves. The fine variety of Gynostemma pentaphyllum is cool and sweet. Modern Gynostemma pentaphyllum research experts and medical experts basically write Gynostemma pentaphyllum as a bitter variety. No wonder people basically misunderstand that Gynostemma pentaphyllum has the same function, and there is no difference between good and bad, so the genuine product is the genuine product.
Wild Gynostemma pentaphyllum, the king of Gynostemma pentaphyllum, is cool and sweet. It naturally grows in sparse forests, hilltops, stone piles and roadsides in mountainous areas above 1000 meters above sea level. It brings together the essence of the sun and the moon for many years and is a rare plant thanks to rain and fog. It contains 8%- 12% gypenosides. The longer the growth time, the higher the saponin content. In China, Gynostemma pentaphyllum is the same, which has strong medicinal and health care functions. A good variety planted on low altitude flat land will greatly reduce its efficacy.
What is glycoside? Glycosides are condensed from various sugar and non-sugar organic compounds. Generally speaking, they are mostly white crystals, also known as sugar conjugates, sugar conjugates or glycosides.
Three varieties of cucurbitaceae are not Gynostemma pentaphyllum. American scientists call them three varieties. In fact, they are: A, Petunia, B, Chardonnay, also known as Ciba, C and Ma Tongling. They are very similar to Gynostemma pentaphyllum, but there are strict differences.
Chemical constituents of Gynostemma pentaphyllum;
L, Saponins: The main chemical component is Gynura divaricata saponin, the basic chemical structure is the same as ginsenoside, belonging to tetracyclic triterpenoid dammarane saponin. At present, more than 80 kinds of saponins have been isolated, of which more than 72 kinds have extensive effects on human body. 2. Other chemical components are:-,sugar: 2, 18 amino acids: aspartic acid, threonine, serine, etc. ; 24 kinds of trace elements: iron, calcium, copper, selenium, etc. ; Fourth, vitamins; 5. Malonic acid; Flavonoids: a, rutin, b, Phytolacca acinosa. The molecular structure of: 3,4,8, 12 of Gynostemma pentaphyllum saponin is the same as that of: RB 1, RB3, RD, RF2 of ginsenoside, and the molecular structure of the other 1 1 is very similar, so it is called South Ginseng.
Gynostemma pentaphyllum's contribution to mankind;
With the progress of science, people pay more and more attention to the medicinal and health care functions of Gynostemma pentaphyllum. Japanese scientists have made remarkable achievements in the treatment of lowering blood fat, cholesterol and cardiovascular and cerebrovascular diseases. American scientists have found that they have special effects in reducing the number one killer of human beings-hypertension, arteriosclerosis, cardiovascular and cerebrovascular diseases and so on. After more than ten years' research, we have obtained the formula patent with Gynostemma pentaphyllum. Gynostemma pentaphyllum's special contributions to human beings are as follows: First, it improves a series of metabolism of human body functions, promotes the normal operation of human body functions and protects people's health. If people's metabolic function is disordered, people will get sick. Second, Gynostemma pentaphyllum has seven bidirectional regulating effects: 1, hypertension and hypotension; 2. The human body is too fat and too thin; 3. Regulation of heart rhythm, bradycardia and tachycardia; 4. Lipid metabolism; 5. Too many true red blood cells and too few; 6. Too many platelets and too few white blood cells; 7. When the immune system is adjusted to normal, it will automatically stabilize. Third, remove the lipid and other attachments on the intestinal wall, stomach wall and blood vessel wall to soften blood vessels. Continue to take it for one year to consolidate the curative effect without rebounding. Fourth, prevent and reduce the number one killer of mankind: hypertension, arteriosclerosis, cardiovascular and cerebrovascular diseases; No.2 killer: prevention and treatment of cancer and tumor: Gynostemma pentaphyllum can directly kill sarcoma: it can significantly inhibit the growth of cancer cells, and has inhibitory effects on tumors such as liver cancer, lung cancer, uterine cancer, melanoma, esophagus, breast, rectum and skin; It has no effect on normal cell proliferation; Prevent normal cells from becoming cancerous, promote the self-healing ability of cells and guide cancer cells to return to normal. Changing oncogenes, although the causes leading to tumors are complex and varied, the most important change is the infinite proliferation of tissues and cells caused by the mutation of cell RDS gene. The part that controls gene changes is the shortening of DNA short chains. If the short chain length returns to normal, the tumor cells can be reversed and return to normal cells. However, western medicine mainly uses surgery, radiotherapy, chemotherapy and other methods to treat tumors, all of which have defects. First, only early patients can have surgery; Second, radiotherapy has obvious limitations; Third, chemotherapy has many side effects. It kills a large number of normal cells while killing tumor cells, which seriously damages the immune system and leads to the loss of control in the later stage of tumor. Cause recurrence and metastasis. Tea polyphenols and catechins in the patented formula can induce cancer cells to "commit suicide" and cause apoptosis; It also has the function of "strengthening the body resistance and eliminating evil", which is a new concept of cancer treatment in contemporary Chinese medicine. Killer 5 and 3 prevent and treat diabetes, activate and regenerate islet β cells, secrete insulin normally, reduce blood sugar and urine sugar in a balanced way, and improve the utilization rate of insulin by human tissues and cells. Sixth, the prevention and treatment of obesity. Gynostemma pentaphyllum is the number one, number two and number three killer of human beings and a powerful nemesis of obesity. At the same time, it has the functions of protecting liver and kidney, preventing and treating colds and various stomach diseases, inhibiting respiratory tract and digestive tract 10 pathogens, effectively preventing and treating colds, pneumonia, bronchitis and digestive tract diseases, and alleviating hepatotoxicity. Gynostemma pentaphyllum can make a great contribution to the protection of human health, and it will be even greater if it is formulated scientifically. For example, even if Gynostemma pentaphyllum is taken for many years, it cannot prevent and treat diseases, and the prepared Gynostemma pentaphyllum compound tea has special effects.
After more than ten years of amateur research, the author successfully invented "Wild Gynostemma pentaphyllum Compound Tea" and applied for a patent in China National Intellectual Property Administration on 1998. In the same year, I received the admission notice and the first-instance qualified notice. In March, 2000, I received the Notice of Substantive Examination with the patent application number of 98 1 18059.0, and sent a batch of compound teas for China National Intellectual Property Administration to identify. The conclusion of China National Intellectual Property Administration's evaluation is: "This compound tea is a kind of medicinal health tea, which has the functions of strengthening body resistance and eliminating pathogenic factors, clearing away heat and toxic materials, preventing and treating cancer, eliminating phlegm and relieving cough, balancing blood pressure, weight and heart rhythm. Reduce blood pressure, blood lipid and cholesterol. Improve metabolism, calm central nervous system and protect liver and kidney; Prevention and treatment of cardiovascular and cerebrovascular diseases. Black hair, hair growth, black beard, alopecia prevention, anti-fatigue and anti-aging effects. It can automatically stabilize under the conditions of low blood pressure, high blood pressure, fat weight loss, thin weight gain, bradycardia and normal tachycardia, without stopping tea. It has unique effects on old and new gastropathy, stimulating appetite, preventing and treating cancer and tumor, coronary heart disease, myocardial infarction, diabetes, obesity, people who don't eat after drinking, bronchitis, common cold, heatstroke (cyanosis) and so on. It is effective for urinary calculi, gallstones, hepatitis, etc. And it is disease-free and healthy, filling the gap at home and abroad. " Published in the 6th issue of Patent Implementation Information in 2000, and included in the "National Key Promotion Project". In 200 1 year, China National Intellectual Property Administration officially granted the patent right, and sent the patent certificate in 1 1 year. The compound tea is superior to other Chinese and western medicines in treating cardiovascular and cerebrovascular diseases, such as hypertension, hypotension, coronary heart disease, myocardial infarction, arteriosclerosis, diabetes, cancer, tumor, obesity and gastropathy. When the above-mentioned diseases are ineffective in large and small hospitals, this compound tea can be quickly cured, and after one year of consolidation, it will not rebound without special circumstances. If former Russian President Yeltsin can treat them at 1999 1655. So far, many lives have been saved.
Rare propagation methods and high-yield cultivation techniques were developed for wild Gynostemma pentaphyllum varieties, while maintaining the wild medicinal efficacy. The success of this research achievement: 1. It has opened up new financial resources for people in alpine mountainous areas suitable for planting Gynostemma pentaphyllum, and achieved the goal of getting rich as soon as possible, planting once and harvesting once with scientific methods. After that, the yield will increase year by year as long as weeding, intertillage and fertilization are strengthened every year. 2. Provide high-quality Gynostemma pentaphyllum as the main raw material for running the factory well. Make the factory more prosperous to meet the needs of human health. 3. Opening up new sources of revenue for the national finance will increase a lot of revenue for the national finance.
According to Hunan Science and Technology News1June 1998 1 1 the fourth edition, before 1993, the price per kilogram of 5 yuan changed, resulting in an excessive backlog of Gynostemma pentaphyllum, from 1994 to 1997 for almost four years. At the beginning of 1998, some foreign businessmen came to Suining county of our province to order Gynostemma pentaphyllum, which was shipped in previous years, but the transaction price was the horizontal shop of 5 yuan, Xinning and Huangshunshan per kilogram, and the purchase price was 3.6 yuan per kilogram, at 1997. 1998 rose to 5 yuan a kilogram in spring. 1995, we successfully developed the "Wild Gynostemma pentaphyllum Compound Tea", and received a small number of responses from relevant personnel in Changsha, Shaoyang, Guangdong, Foshan, Guilin and Xinjiang. It has begun to attract people's attention again. 1in August, 1998, l998 applied for a patent, and was immediately notified to accept it. On June, 5438+0 1 obtained the notice of first instance. Immediately, the quality Gynostemma pentaphyllum in Hengpu and Huangshunshan rose to 12 yuan per kilogram, and now it has risen to 14 yuan per kilogram. This is because the harvesting method and season are wrong, and harvesting a place will destroy the provenance of a place, leading to the basic extinction of precious resources, which requires more scientific methods and artificial cultivation.
In 2000, China Science and Technology and Talent Development Center appraised me as a special researcher of "World Science and Technology Expert" and won the trophy of "Contributor to Scientific and Technological Progress". The research results are included in World Science and Technology Experts (China Volume).
200 1 65438+2 China international exchange publishing house and China science and technology research and exchange center were rated as "world outstanding experts" and "special researchers", and their achievements were included in the "list of world outstanding experts"; In the autumn of 200 1, the International Patent and Technological Achievements Expo in London, England awarded the gold medal of "Wild Gynostemma pentaphyllum Compound Tea", and London Institute of Applied Technology accepted him as a researcher and was rated as a senior researcher. Its achievements were included in the Dictionary of World Inventors and Excellent Patents (20th century edition). In May, 2002, People's Daily Publishing House and China Science and Technology Research Association included his scientific research achievements in China Talent Dictionary. In June 2002, the Cultural Market Development Center of the Ministry of Culture listed his scientific and technological achievements in China Century Talent Collection. Gynostemma pentaphyllum and human health was awarded the first prize by China Talent and other three magazines in February, 2000, and was included in the Collection of Excellent Leadership and Management Arts in China. In March, 2002, this paper won the international excellent thesis award in the international exchange selection activities organized by the World Chinese Exchange Association and the World Cultural and Art Research Center. In May, 2002, he won the first prize of the excellent thesis of "China High-tech Industrialization Research Association", and the thesis was included in "China Strategy Library for Rejuvenating the Country through Science and Education". Scientific research achievements were included in the collection of biomedical achievements in China; "Re-discussion on Gynostemma pentaphyllum and human health" won the first prize of excellent papers in China People's Political Consultative Conference and Economic News magazine in August 2002. In June, 2002, China People of Science published his paper Gynostemma pentaphyllum and human health in the book Selected Excellent Papers of Science China Year. In June, 2002, China, together with Asia-Pacific Institute of International Medicine, World Academy of Medical Sciences, Editorial Board of World Medical Experts and World Science Press, jointly reviewed and compiled the Grand Ceremony of World Medical Experts. And awarded the honorary selection certificate with outstanding contributions to society and the honorary title of "World Medical Expert". The scientific and technological achievements of this invention were included in the book "East (Seoul, Korea) and West (Nuremberg, Germany)" in June 2002, and spread to the whole world. In May 2003, Lin Jidong was specially appointed as an expert member of the Expert Committee by the National Institute of Science and Technology. His unit is a strategic alliance unit of our college. His research "Wild Gynostemma pentaphyllum Compound Tea" was awarded as an excellent project, and in April 2003, the Institute of Humanities of Chinese Academy of Management Sciences awarded the first prize of the paper "Gynostemma pentaphyllum and human health". Three companies, including People's Daily Talent Exchange Service Center and China Public Relations Association, rated his scientific research achievements as excellent scientific research academic achievement awards. This achievement won the first prize in the selection of scientific and technological achievements in the new century and the first "Elite Cup" held by Beijing Elite Cultural Development Center. Many of them are included in relevant classics, which are based on book entry, certificate issuance and certificates.