When it comes to health care, people think of "quit smoking and limit alcohol", "eat less fatty meat and animal offal", "don't stay up late", "exercise more" and so on. "and so on," and so on, "a thousand people," the health of the sermon. In fact, not everyone who smokes is prone to lung cancer, the same amount of alcohol is not the same amount of damage to the health of everyone, often "big fish and meat" lifestyle does not necessarily all will happen to obesity or "three highs". This is the universal individual differences.
The development of science, human genetic understanding has made great progress. Research has proved that the essence of the differences between people is the difference in genes. "In addition to the exclusion of injury, almost all the diseases that plague human beings are related to genes", such as hypertension, diabetes, coronary heart disease, tumors and other chronic diseases, in essence, the occurrence of these diseases and the continuous aggravation, is the body and inherent disease susceptibility genes and incompatible environmental factors interacting with the results. Everyone is born with certain disease susceptibility genes, but the size and focus of the risk varies from person to person. Every day, everyone is inevitably exposed to certain environmental factors that are incompatible with their own, including dietary structure, lifestyle, etc., which accumulate over time and lead to the occurrence of chronic diseases.
Since the beginning of this century, there has been significant progress in genetic science, and the technology of genetic testing has become very mature, allowing people to detect potential disease risks early through genetic testing and risk assessment, and providing scientific means for people to achieve personalized health care. The so-called personalized health care, that is, different from each other, targeted health care, so that the health of the focus of the protection, the method is simple and clear, the effect is more significant.
Gene and Tianjikangsheng genetic testing
The human body consists of about 40 to 60 trillion cells. All cells, except mature red blood cells and platelets, have a nucleus, which contains 23 pairs of chromosomes. These 23 pairs of chromosomes originally came from the 23 chromosomes of the father's sperm cells and 23 chromosomes of the mother's egg cells. Scientific research has found that the spiral-like 23 pairs of chromosomes in the cell nucleus consist of about more than 20,000 genes and more than 3 billion base pairs, and that there are four types of bases, A, T, G, and C, which are paired according to certain principles. Genes are these four types of bases arranged in a different order, constituting the code of human life. Research further found that, on average, for every 1,000 base sequences, there is about 1 base sequence arrangement between people have differences, scientists call it "single nucleotide polymorphism (SNP)". Differences in base sequences are differences in genes. We can not underestimate this one-thousandth of the difference, it determines the difference between people and people's looks, height, skin color, fat and thin, personality and so on, but also determines the difference between different individuals on the sensitivity of environmental factors. According to Sung's gene expert Jiang Jun Cheng, some people may smoke for their whole life without getting lung cancer, while some other people who don't smoke or smoke a small amount of cigarettes can't be spared. Some people can drink "a thousand cups" without getting drunk, while others get drunk after one sip of wine. With the same lifestyle or diet, some people are healthy while others get sick. Some people how to eat are not easy to gain weight, while some people "drink water" are very difficult to lose weight. All of these individual differences are specific manifestations of genetic differences.
Human beings have never stopped exploring the mysteries of their own lives. In the early 1990s, by the United States, Britain, Japan, France, Germany and China, six countries scientists **** with the participation of the "Human Genome Project", after 14 years of efforts, invested more than 3 billion U.S. dollars in 2003 was successfully completed. The completion of this great scientific program has enabled mankind's understanding of their own lives to enter a brand new milestone. Tianjikangsheng genetic testing technology is the crystallization of this scientific achievement, which provides a scientific means for human beings to decipher the mystery of life and find individualized health methods.
The value of combining Tianjikangsheng testing with health management
Genetic testing is the analysis of chromosomes, genes and their gene products in the cells of the person being tested through specialized testing equipment, in order to determine whether there is a change in the genes associated with a specific disease or trait. Currently, susceptibility testing for complex diseases focuses on extracting the DNA of cells such as blood or oral mucosa of the tested person, focusing on common single nucleotide polymorphism (SNP) loci related to the occurrence of the disease. Through the disease susceptibility testing, people can know whether their genes contain such dangerous disease-causing factors, and in the future life targeted to improve or adjust their own bad habits and nutritional structure, to achieve the purpose of reducing the risk of disease.
In developed countries, genetic testing has become part of the healthcare delivery system and has been shown to be effective in reducing the risk of disease in individuals while saving healthcare dollars.
Genetic testing is a new method of physical examination that combines genetic testing technology with genetics, preventive medicine, clinical medicine, bioinformatics, health management, nutrition, and health psychology to provide individualized health management and targeted health guidance for the effective prevention and treatment of chronic diseases with a higher degree of scientific validity and a greater degree of foresight. Its value is mainly reflected in the personalized disease prevention and treatment, personalized nutritional health care, personalized health checkup, personalized exercise and personalized medication.
Tianjikangsheng genetic testing is different from regular health checkups. The significance of health checkups lies mainly in the early detection and treatment of diseases, in order to buy time for treatment. The significance of genetic testing lies mainly in the early detection and prevention of disease risk, in order to gain time for prevention. The two cannot replace each other, but can complement each other. The organic combination of health checkups and genetic testing, personalized health management, disease prevention and treatment will avoid the embarrassment and generalization of "one size fits all", and health guidance will be easier for people to accept, and the prevalence of chronic diseases will be greatly reduced, as well as saving healthcare expenditures.
Genetic testing is a technology that provides a scientific basis for disease risk assessment and prediction of susceptibility. Health management, on the other hand, is a systematic methodology that has emerged in recent years to provide a scientific approach to disease prevention and control. The combination of genetic testing and health management can make both of them complement each other, genetic testing has more development power, health management has more vitality, *** with a better prevention of sub-health, improve the health level of the public to play a greater role. Tianji Kang Sheng genetic testing and Sheng's research and selection of health management combined with a new health service model, must be the direction of future development, the future is very bright.
Tianji Kangsheng testing core service management tools
Genetic testing, as an emerging means of service in the health industry, can fill the gaps in clinical and traditional prevention and treatment, and has broad prospects for development. However, in recent years, the market has seen the emergence of many genetic testing companies, whose service quality and level of service is uneven, which is a mixed blessing for the market. Because it is still temporarily unable to form a standardized industry standards, Sheng's Tianji Kangsheng Jiang Juncheng reminded people that some specific issues need to be worthy of attention.
First, the basis and standards of the genetic loci selected by the various testing organizations are often separate, these candidate genes and loci are suitable for the Chinese population, whether they have been verified by a large sample of the Chinese population? Racial differences, environmental differences, differences in lifestyle, differences in dietary structure and other factors should be used as important references for the selection of genetic loci. In addition, the number of loci selected is not necessarily greater, but rather whether they are more relevant to the disease and whether the means of intervention is clearer.
Second, there is a big difference in accuracy and cost depending on the testing technology used. For example, microarray technology can better reduce the cost and improve the speed of detection, but how to control the false-positive or false-negative results that are likely to occur, and thus ensure the accuracy of the test results. Once genetic testing lacks reliability and accuracy, the consequences of misjudgment are often severe.
Third, whether the gene symbols, detection sites and genotyping results listed in the genetic test report are clearly shown. At the same time, the description of the function of these genes, the risk of "defective" genes is clearly described, the correspondence between the gene and the disease is clear, and the risk of intervention is clear. These are all information that the examinee has the right to know.
Fourth, the genetic testing company has no professionally trained post-test health service professionals. When the examinee holds a genetic test report of "a test for life", there is no professional interpreter to carry out "one-on-one" interpretation, and put forward a precise health management guidance program, so as to ensure that the examinee's satisfaction with the genetic test service. It is important to know that the genetic risk of a disease shown in the report is not equal to the risk of being susceptible to the disease, and whether or not a disease occurs is also related to the environment. The core of interpreting the report is to analyze and evaluate the risk of disease susceptibility based on the genetic risk of the examinee, combined with the lifestyle, dietary structure, exercise and psychological and other environmental factors, to provide focused health management guidance by providing early warning of disease. Analyzing and interpreting genetic test reports requires not only knowledge of genetics, but also knowledge of clinical medicine, preventive medicine, nutrition, health management, health psychology, and kinesiology, as well as a certain amount of practical experience. Therefore, it is very difficult for the average patient to read a genetic test report, and even clinicians need to be trained.
Fifth, whether the personalized health management of the examinee can be carried out permanently, and whether there is a set of more perfect post-test health management service system. Each year, we need to conduct one or two comprehensive health risk assessments based on the new health examination results of the examinee, combined with genetic testing data and relevant environmental factors, to adjust and improve health practices in a timely manner, and to ensure a positive trend in health.
Sixth, whether the promotion and publicity of the genetic testing company is standardized. The role of genetic testing is easily exaggerated by unscrupulous merchants, and there is no cure for all diseases in the world.
Seventh, the price of charges. At present, many genetic testing organizations charge more chaotic standards, some of them are very high, up to tens of thousands of dollars or even hundreds of thousands of dollars. And some are very low, a test dozens of hundreds of packages even as low as a few hundred dollars. It is not normal to charge too much or too little. Genetic testing fees should be based on the Price Bureau announced the "deoxyribonucleic acid (DNA) sequencing method" charges, this testing technology represents the gold standard of genetic testing, according to the actual test site reasonable fees, the accuracy and reliability of the test, but also for the post-test services to provide the necessary support. From a market economy point of view, there is no reasonable profit, where there is reliable service.
Therefore, Sheng's Tianji Kangsheng genetic testing and Sheng's research and selection of health management not only by the general public's attention, but also by the national government at all levels of support. This new technical service will certainly promote the development of health, bring new health services to the public, effectively control the incidence of chronic diseases, and improve the level of health.