The pathogenesis, prevention and treatment of oral plaque diseases
The research group focuses on the following two common oral plaque diseases: caries and periodontal disease:
Formation and developmental characteristics of oral biofilm
Regulation of virulence factors of caries-related acid-producing bacteria and development of anti-caries vaccines
Research on periodontal pathogenic bacteria Pathogenesis and the host’s natural and adaptive immune response to periodontal pathogens
Research on oral and maxillofacial development and genetic diseases
Establishing an oral genetic disease diagnosis and resource collection network in Hubei Province , discover disease families, summarize the data, and establish an oral genetic disease resource database. Locate the disease-causing loci through linkage analysis, clone the disease-causing genes, and reveal the pathogenesis.
Research on oral and maxillofacial tumors
This research group focuses on the pathogenesis and treatment of oral cancer, odontogenic tumors and vascular diseases, focusing on the following research:
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Research on the molecular regulatory mechanism of the occurrence and development of hemangiomas
Clinical and basic research on giant vascular malformations in the oral and maxillofacial region
Research on giant cystic lesions of the jaw Clinical and basic research
Molecular mechanisms of angiogenesis and cervical lymphatic metastasis during the growth and metastasis of oral cancer
Mechanisms of oral and maxillofacial pain and dysfunction
This research group is mainly engaged in research on the pathogenesis of oral and maxillofacial pain and dysfunction. The main research contents include establishing animal models of temporomandibular joint and isolating synovial fluid diagnostic markers for temporomandibular joint disorders, establishing synovial stem cell lines and synovial fluid Research on joint tissue engineering of membrane stem cells, salivary gland endoscopy combined with modern molecular biology techniques for diagnosis and treatment of chronic recurrent sialadenitis, and treatment of trigeminal neuralgia.
Tooth and oral and maxillofacial repair biology
This research group conducts research from the aspects of dental aesthetic repair, implant surface coating, bone repair biomaterials, new dentin bonding materials, etc. An exploratory study of the biology of oral and maxillofacial prosthetics.