I. OVERVIEW
Numerical simulation technology has made great progress due to the rapid improvement of computer level and software capability. Models of the head, brain and blood vessels have been developed to study head injury mechanisms and injury protection. The finite element method is an important method to study the mechanism of human tissue injury. Due to the complexity of human tissue structure, how to establish a finite element model with high biosimilarity is the primary problem that must be solved in the finite element computation; secondly, how to solve the highly nonlinear, fluid-solid coupling problems in numerical simulation is the key to finite element simulation.
Based on the above difficulties, ZOOMLIKE provides researchers with a set of complete solutions from 3D image modeling to finite element numerical simulation.
Simpleware and ADINA joint simulation technology
Simpleware software is a set of integrated reverse engineering, materials engineering, biomechanical engineering, finite element analysis and other multi-industry, multidisciplinary fields of the unified solution of the professional software, it is through the three-dimensional body map or two-dimensional planar sequence of images (CT/MRI/Microscope), it is the first time that the three-dimensional body map or two-dimensional planar sequence of images, it is the first time that the three-dimensional body map or two-dimensional planar sequence of images is the key to the finite element simulation.
ADINA is one of the most famous general-purpose finite element analysis software in the world. ADINA is a global leader in the theory of computation and a wide range of problem solving, especially for structural nonlinearities, fluid/solid coupling and other complex problems with a strong advantage, and is regarded by industry insiders as a precursor to the direction of nonlinear finite element development, and has been widely used in engineering simulation calculations in various industrial fields, including civil engineering and engineering simulation calculations, including civil engineering and engineering simulation calculations. It is widely used in various industrial fields, including civil engineering, transportation, petrochemical, machinery manufacturing, aerospace, automotive, defense industry, shipping, biomechanics, and scientific research.
Using Simpleware and ADINA joint simulation technology, ZOOMLIFE technical engineers can create three-dimensional models from CT/MRI two-dimensional tomography data of human tissues, and use Simpleware's advanced mesh dissecting technology to generate ADINA structural and fluid models. ADINA's powerful nonlinear mechanical computation functions and fluid-structure coupling solving capabilities efficiently and accurately simulate organizational stress, strain, heat transfer, fluid dynamics, and other problems.
Three, Simpleware software in human tissue modeling application introduction
Simpleware software human tissue modeling function greatly promotes the development of medical research and clinical medicine. in June 2015 in the imitation science and technology was invited to participate in the Harbin Institute of Technology 3D image digital modeling and finite element analysis software Simpleware numerical simulation technology symposium. Simulation technology symposium. Simpleware software was introduced in detail, and the application of Simpleware software in related fields was introduced in detail and case operation. For example, the human body structure modeling, blood fluid dynamics calculation, cardiac fluid-structure coupling simulation calculation and so on.
Calculation of hydrodynamics of cerebral spinal cord
Based on the MRI images, Simpleware is used to reconstruct the 3D model and establish a 3D hydrodynamic finite element model of the cerebral spinal cord located in the central nervous system. In this case, the flow of the cerebral spinal cord and the deformation of the brain tissue in the circulatory system need to be calculated, so the calculation needs to invoke the ADINA-FSI solver (fluid-solid coupling)Fluid-solid coupling calculation of cerebral aneurysm
? Cerebral aneurysms are pathological swellings of arteries, typically found in the anterior and posterior portions of Willis' ring. Rupture of a cerebral aneurysm can cause subarachnoid hemorrhage as well as serious complications. Therefore, hemodynamics plays a very important role in the analysis of ruptured cerebral aneurysms. The following example simulates the blood flow and the fluid-solid coupling problem. The model is built using 3D image processing techniques, and the non-Newtonian incompressible fluid, fluid-solid coupling solver in ADINA is selected.
Fluid-solid coupling simulation of the heart
Most of the motion processes of biological tissues are related to fluid-solid coupling. This example uses the fluid-solid coupling computational method to simulate a model of the right and left atria and diaphragms of a particular patient, with the goal of using it to optimize the surgical operation of the pulmonary valve of the heart.Fluid-Solid Coupling Simulation of an Aortic Valve
This example uses ADINA to model the aortic root and aortic valve in two-dimensional plane strain, with a weakly compressible fluid and a given pressure of 14 mmHg at the inlet.
Progressive destruction of lumbar intervertebral discs predicted by porous elastic finite element model
Lumbar intervertebral disc herniation is one of the more common disorders, mainly due to the fact that all parts of the lumbar intervertebral discs (nucleus pulposus, annulus fibrosus, and cartilaginous plate), especially the nucleus pulposus, have different degrees of degenerative changes, and then the annulus fibrosus of the disc ruptures under the action of external factors, the nucleus pulposus tissue protrudes from the rupture place (or prolapse) in the posterior or the spinal canal, resulting in the adjacent spinal nerve roots suffer from irritation or compression, thus producing a series of clinical symptoms such as lumbar pain, numbness and pain in one or both lower limbs. The complex modeling of the lumbar intervertebral disc is the focus of finite element analysis.
The intervertebral disc is modeled using a porous media material and considering both solid and liquid phases. The following figure shows the finite element model of lumbar intervertebral disc. Simpleware provides a variety of image processing tools to extract a 3D model from a 2D CT/MRI image.
After a cycle of loading, the force on each part versus time is shown below.
At the same time, we can also obtain the effective stress cloud of the intervertebral disc under different loading force and cycle number conditions.
The joint simulation technology of Zoomfoam Simpleware and Zoomfoam ADINA provides an efficient solution for image processing - finite element model generation - finite element calculation.