Taiwan Biotechnology Exhibition GoldMed New Generation Handheld Needle-Free Liquid Drug Delivery System
The modern love of beauty is no longer the monopoly of women, and now even men are very concerned about the maintenance of many medical procedures may use needles or cause minimally invasive wounds, which results in the treatment of parts of the red, hot, swollen, painful, and even bleeding, and requires a period of recovery. Some of them will resist the treatment with needles or do not like the side effects caused by the operation, and GNT Biotech&Medical Devices Corporation (GNT Biotech&Medical Devices Corporation) launched this non-needle, non-invasive and non-recovery period of the treatment meets the customer's this demand.
Introduction to Needle-Free Liquid Medication Injectors
Needle-free liquid medication injectors date back to the 1800s, when they were used to treat or ameliorate clinical problems such as neuralgia, and more recently in the 1930s, when the technology became more sophisticated and began to play an important role in human clinical care. The technology has become more sophisticated and has begun to play an important role in human clinical care, especially for vaccination and immunization, and for individuals who require long-term use of insulin or growth hormones.
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This type of syringe can be broadly categorized into two types, which are single-use disposable cartridge jet injectors (Disposable Cartridge Jet Injectors; DCJIs), and multi-use nozzle jet injectors (Multi-use nozzle Jet Injectors; MUNJIs). (MUNJIs), this type of mechanical operation, most of the spring or pressure inert gas as the delivery power source, on the delivery of liquid drugs to form a high-pressure water column, at a certain speed, the drug molecules through the skin barrier, delivered to the organism. As the skin is the human body against the external environment of the first line of defense, especially the closest to the surface of the epidermis is very dense structure, so the delivery of drug formation speed and water column diameter size is able to cross the epidermis into the organism is one of the important indexes, the general requirements for delivery of the pressure of the water column speed to be greater than 100 m / s, while the water column diameter size of the conditions of the 76-360 μm between the opportunity to cross the epidermis.
Different delivery power sources have different advantages, the biggest advantage of using spring power is that the equipment is relatively small, durable and low-cost, but it also limits the range of delivery power and the flexibility of use, especially in different parts of the human body skin has a different modulus of elasticity (Young's modulus), the size of the delivery power needs to be adjusted accordingly to ensure the delivery of drugs. In particular, different parts of the human skin have different modulus of elasticity (Young's modulus), and the size of the delivery power needs to be adjusted accordingly in order to ensure the effectiveness of drug delivery. Gas power happens to have excellent flexibility in use, and the delivery power can be adjusted according to the mechanical properties of different parts of the skin, which also allows for delivery of a larger volume of medication. The Centers for Disease Control and Prevention (DCD) suggests the use of multiple-use nozzle syringes for vaccine delivery if there is a risk of large-scale blood-borne infectious disease spreading, or a national influenza pandemic, or a biochemical attack.
Water column type needleless drug delivery devices certainly have a certain degree of convenience, but the acceptance of the evaluation is quite poor evaluation, generally although the needleless syringe is considered to be more comfortable, but about 30% of the users said that there is immediate or delayed pain, redness, swelling, burning sensation, and bleeding phenomenon, resulting in a long-term need for injections of the user acceptance is limited, so the development of a new liquid drug delivery mechanism will be the most important. The development of new liquid drug delivery mechanisms will be a challenge for this type of medical device in the future.
GoldMed? Needle-Free Liquid Drug Delivery System - A New Type of Liquid Drug Delivery System
The Needle-Free Liquid Drug Delivery System (NDLDS) developed by HUAZEN Biomedical is different from the general water column drug delivery method, which mainly utilizes the delivery of gas molecules made up of powered gas (carbon dioxide or nitrogen) and liquid molecules made up of liquid drug delivery. The liquid-phase molecules of the drug are mixed with the liquid-phase molecules of the drug in the pressurized drug delivery tube (venturi), and the liquid particles are atomized at the same time to make the liquid particles tiny, but can generate enough momentum to penetrate the skin, so that although the particles are fine, there is no need for additional carrier to assist in the delivery of the drug, GoldMed can deliver not only general liquid drug molecules, but also nano-gold with a particle size of 600 nm or less, and molecular weight of 80km. In addition to delivering general liquid drug molecules, GoldMed? can also deliver nano-gold with a particle size of 600nm or less and hyaluronic acid with a molecular weight of 80kDa or less, with a delivery depth up to the dermis.
In addition, in a diabetic wound healing trial, GoldMed was used to deliver a healing formula, and the results of the trial showed that GoldMed not only did not cause further damage to diabetic wounds that would prevent healing, but instead, it was able to effectively promote diabetic wound healing due to the deeper delivery of the formula ingredients, which demonstrated the superior product characteristics.
Golden skin Maintenance of new choices
Maintenance of recent years, blowing the wind of luxury, the major brands use precious stones and minerals to join the maintenance of the product, hope that the formation of these precious elements of the energy, but also for the skin to be utilized to assist in the maintenance of the skin, and even delay the skin aging, the commonly used materials are crystals, diamonds, tourmalines, pearls, amber, malachite, and other materials, as well as the use of the skin to protect the skin. The commonly used materials are crystals, diamonds, tourmalines, pearls, amber, malachite, etc. Of course, precious metals are also used, with platinum and gold being the most common. Specific evidence of the relationship between gold and cosmetology can be found in gold implant surgery. The main task of the dermis is responsible for the skin's firmness and elasticity, in Europe, plastic surgeons buried tiny gold wire in the dermis of the skin, by the presence of a foreign body, *** collagen proliferation, such *** just to make up for because of aging, the gradual decline of collagen production mechanism, collagen content increases, the skin naturally return to the firmness of the elasticity of the wrinkles, but also have a more smooth The newest addition to the lineup is a new, more advanced version of the original, which is now available in a variety of colors and sizes.
Physical Nanoparticles for Diabetic Wound Healing
Physical Nanoparticles are a new partner in post-surgical care for minimally invasive procedures in aesthetic medicine, making skin care a much simpler exercise. The physical nanoparticles are a new partner for post-surgical skin care, making it easier for people to take care of themselves. Experiments in tissue engineering have confirmed that the nanoparticles have the ability to proliferate fibroblasts and increase collagen production, as well as promote the absorption and utilization of active ingredients, which not only allows for twice the amount of skin care, but can also be used to promote wound healing in diabetes. The results of a wound healing assessment program conducted by Director of Fu Jen Catholic University's Center for Interdisciplinary Research in Medicine and Optoelectronics, Mr. Leung Yiu Jen, showed that the use of a combination of catechins, alpha lipoic acid, and physical nano-gold had a beneficial effect on wound healing in general, and even in diabetic wounds. Wounds were made on the backs of diabetic rats, and formulations containing different active ingredients were applied to the wounds once a day for seven days to observe wound healing. The results showed that the combination of formulations containing physical nano-gold significantly promoted wound healing in diabetic rats, and that in addition to assisting in wound healing through antioxidant and anti-inflammatory effects, the presence of physical nano-gold In addition to the antioxidant and anti-inflammatory effects of the formula, the presence of physical nano-gold enhances the absorption of the active ingredients into the skin and increases the utilization of the active ingredients by the cells, thus allowing the combination of the formula to achieve the optimal efficacy in promoting wound healing on the body surface.
Topics: Noninvasive, Gold