Briefly describe the major sources of radionuclides for medical applications.

Answer: radionuclides for clinical applications can be obtained through gas pedal production, reactor production, extraction from fission products, and radionuclide generator drenching.

Accelerators accelerate charged particles such as protons, tritium nuclei, and alpha particles, which bombard a variety of target nuclei, causing different nuclear reactions that produce a variety of radionuclides. Radionuclides produced by gas pedals commonly used in medicine include 11C, 13N, 15O, 18F, 123I, 201Tl, 67Ga, 111In, etc.

The reactor is the strongest neutron source, the use of nuclear reactors powerful neutron flow bombardment of a variety of target nuclei, can be a large number of radionuclides used in nuclear medicine diagnosis and treatment. Radionuclides produced by reactors commonly used in medicine include 99Mo, 113Sn, 125I, 131I, 32P, 14C, 3H, 89Sr, 133Xe, 186Re, 153Sm, and so on.

Nuclear fuel irradiation produces more than 400 kinds of fission products, with only a dozen or so having practical extractive value. The fissionable nuclides that have significance in medicine are: 99Mo, 131I, 133Xe, etc.

The radionuclide generator is a device that separates the short half-life daughter from the long half-life parent, also known as the "mother cow". Its emergence makes the application of certain short half-life nuclides possible, and its easy to use, widely used in medicine. Generators commonly used in medicine are: 99Mo-99mTc generator, 188W-188Re generator, 82Sr-82Rb generator, 81Rb-81mKr generator and so on.