Yutin Instructions
Drug Name
Trade Name: Yutin
Generic Name: Levonorgestrel Tablets
English Name: Fat Emulsion Injection
Ingredients
Each tablet of this product contains the main ingredient levonorgestrel 0.75 mg. Excipients are starch, lactose, sucrose, dextrin, magnesium stearate, sodium carboxymethyl starch.
Indications
It is used for emergency contraception in women, i.e., when unprotected or other contraceptive methods fail by chance.
Dosage
Oral, take the first tablet within 72 hours after intercourse and the second tablet 12 hours later.
Adverse effects
1. Menstrual changes can be seen, most of them are manifested as early or delayed menstruation in the month when the drug is taken. 2. Mild nausea, vomiting, breast tenderness, headache, dizziness, fatigue, and other symptoms, usually do not need to be dealt with, and can be disappeared after 24 hours, such as the symptoms of the more serious or persistent should be consulted to the physician. 3. Abnormal uterine bleeding can be observed, and if the bleeding does not disappear, you should go to the hospital.
Contraindications
It is contraindicated in known or suspected pregnancy.
Breast cancer, cancer of the reproductive organs, abnormal liver function or recent history of liver disease or jaundice, venous thrombosis, cerebrovascular accidents, hypertension, cardiovascular disease, diabetes mellitus, hyperlipidemia, patients with mental depression and women over 40 years of age are contraindicated.
Precautions
1. This product is an emergency remedial contraceptive used for contraceptive errors, not induced abortion. 2. This product can not be used as a regular contraceptive method, and is not recommended for frequent use, and should be used as a reliable contraceptive until the next menstrual period. 3. If vomiting occurs within 2 hours of taking the drug, a replacement tablet should be taken immediately. 4. If the menstrual period does not come after a week of overstaying, there is a possibility of pregnancy. A pregnancy test should be performed or a physician should be consulted.5. If irregular uterine bleeding or severe lower abdominal pain occurs about 3 to 5 weeks after taking the drug, a physician should be consulted to rule out ectopic pregnancy.6. This product is intended for use by persons 17 years of age or older, and persons younger than 17 years of age should consult a physician if they need to use it.7. It is recommended that nursing mothers suspend breastfeeding for at least 3 days after taking the drug, during which time the milk should be expressed at regular intervals.8. Allergic to this product is prohibited, allergic
Special populations Medication
Children Precautions:
Precautions during pregnancy and lactation:
Pregnant women and lactating women are prohibited.
Precautions for the elderly:
Drug interactions
Drug interactions may occur if used concomitantly with other medications (especially phenobarbital, phenytoin sodium, rifampicin, carbamazepine, macrolide antibiotics, imidazole antifungals, cimetidine, and antiviral drugs, etc.), please consult your physician or pharmacist for details.
Pharmacological effects
This product is a rapid-acting, short-acting contraceptive, contraceptive mechanism is to significantly inhibit ovulation and prevent the implantation of the pregnant egg, and increase the consistency of the cervical mucus, the resistance to sperm penetration, thus playing a role in rapid-acting contraception.
Storage
Keep away from light and sealed.
Expiry date
60 months.
Approval number
State Drug License H10983129
Revision date of the instruction
2006/12/25 0:00
Manufacturer
Name of the company: Beijing Zizhu Pharmaceuticals Ltd. Address of the production: No. 27, Chaoyang North Road, Chaoyang District, Beijing Tel. 62250612 If you have any questions, please contact the manufacturer
Introduction to Yutin
Ingredients
The main ingredient of this product is levonorgestrel 0.75 mg per tablet. Excipients are starch, lactose, sucrose, dextrin, magnesium stearate, sodium carboxymethyl starch.
Properties
This product is a white tablet.
Class of action
This product is an over-the-counter drug medication in the category of oral contraceptives.
Indications
It is used for emergency contraception in women, i.e., when unprotected or other contraceptive methods fail by chance.
Specifications
0.75 mg.
Dosage
Take the first tablet orally, within 72 hours of intercourse, and the second tablet 12 hours later.
Adverse effects
Changes in menstruation can be seen, mostly in the form of early or delayed menstruation in the month in which the medication is taken.
Mild nausea, vomiting, breast tenderness, headache, dizziness, fatigue and other symptoms can be seen, usually do not need to be dealt with, can disappear after 24 hours, if the symptoms are more serious or persistent should consult a physician.
Abnormal uterine bleeding may be present, and if the bleeding does not go away on its own, a hospital visit should be made to alert the presence of ectopic pregnancy.
Contraindications
It is contraindicated in breast cancer, cancer of the reproductive organs, abnormal liver function or recent history of liver disease or jaundice, venous thrombosis, cerebrovascular accidents, hypertension, cardiovascular disease, diabetes mellitus, hyperlipidemia, psychiatric depression, and in women over the age of 40.
Precautions
1. This product is an emergency remedial contraceptive for contraceptive errors, not an induced abortion.
2. This product should not be used as a regular contraceptive, and reliable contraceptive measures should be taken after taking the drug until the next menstrual period.
3. If vomiting occurs within 2 hours after taking the pill, 1 additional tablet should be taken immediately.
4. This product may cause the next menstrual period to be early or delayed, if the menstrual period still does not come 1 week after the expiration date, you should go to the hospital immediately for examination to rule out pregnancy.
5. This product is prohibited for those who are allergic to this product, and should be used with caution in allergic individuals.
6. The use of this product is prohibited when the properties of the product have changed.
7. Keep this product out of the reach of children.
8. If you are using other drugs, consult your physician or pharmacist before using this product.
Drug interactions
Drug interactions may occur if used concurrently with other medications (especially phenobarbital, phenytoin sodium, rifampicin, carbamazepine, macrolide antibiotics, imidazole antifungals, cimetidine and antiviral drugs, etc.), please consult your physician or pharmacist for details.
Pharmacological effects
This product is a rapid-acting, short-acting contraceptive, contraceptive mechanism is significantly inhibit ovulation and prevent the implantation of a pregnant egg, and increase the consistency of cervical mucus, sperm penetration resistance increases, so as to play the role of rapid-acting contraception.
Storage
Keep away from light and sealed.
Packaging
Aluminum-plastic packaging, 1 tablet per plate, 1 plate per box.
Effective period
60 months
Execution standard
Chinese Pharmacopoeia, 2010 Edition, Part II
Approval number
State Drug License H11021372
Manufacturer
Beijing Zizhu Pharmaceutical Co. October 01, 2010
A number of common misconceptions in the use of Yutin
Myth 1: The menstrual cycle will be seriously disturbed after taking emergency contraception
Clinical verification has proved that 70% of the women who take Yutin will have their next menstrual period on time, and 80% of the women will not have any significant change in the number of days of the period or the amount of menstruation. A small number of women will have early or late menstruation, and it is normal to have early or late menstruation for about 7 days.
Yutin and other emergency contraceptive pills mainly through the inhibition of ovulation, preventing the sperm and egg combination, to prevent the birth of contraception, taking levonorgestrel as a component of the emergency contraceptive pills is the most common is the advancement of menstruation, the advancement of menstruation from the medicine is also known as the withdrawal of the bleeding, itself, although there is the characteristics of the menstruation, but in fact, not the real menstruation. Yuktin works as an emergency contraceptive because it is a virtual menstruation. Virtual menstruation? to complete, so taking emergency contraceptive pills after menstrual changes is normal, may be due to individual differences and the performance of the obvious or not obvious, after stopping the drug within a short period of time that is back to normal, so do not worry about emergency contraceptive pills will disrupt the menstrual cycle. The World Health Organization and the national family planning department to promote the use of levonorgestrel emergency contraceptive pills for remedial purposes, a major reason is that this drug has a strong reversibility characteristics. Its reversibility is reflected in the fact that signs can return to normal within a short period of time after stopping the pill, and changes in menstruation are no exception.
Myth 2: Yutin and other emergency contraceptives can be eaten at any time
Yutin as an oral drug, in the gastrointestinal tract is well absorbed, 1 hour after the peak of blood concentration can be reached, in order to effectively maintain the concentration of the drug, according to the requirements of the pharmacokinetics, Yutin 72 hours to take, to ideally ensure that the drug's optimal contraceptive effect, and the earlier the period of time, the better. The more you take it, the better it will be.
Emergency contraceptive pills as a new program of family planning in China, has been gradually familiar with the majority of women of childbearing age, but for a long time there has been a lot of use of misunderstanding, resulting in contraceptive failure. The most important thing is to master the time to use the emergency contraceptive pill, that is, 72 hours after the incident, and the earlier the effect of the service, the better, not at any time after the incident can be taken.
The contraceptive mechanism of the emergency contraceptive pill represented by Yutin is to significantly inhibit ovulation and prevent the pregnant egg from implanting, and to increase the consistency of cervical mucus, the resistance of sperm to penetration increases, so as to play the role of quick-acting contraception. This mechanism of action itself determines that the drug must be taken in a timely and effective manner.
In order to give full play to the role of emergency contraceptive pills, in addition to the correct understanding of the use of time, should also pay attention to the following points:
First, if you are already convinced of pregnancy, there is no need to take Yutin and other emergency contraceptive pills. Although it will not affect the health of the fetus or cause miscarriage, but why bother.
Secondly, if you have unprotected sex again after taking Youting, there is still a possibility of pregnancy, because emergency contraceptives are? The first thing you need to do is to get rid of all the pills that you have. If you need emergency contraception at this time, you need to take another emergency contraceptive pill.
Third, some women will have vomiting after taking the pill, remember that if vomiting occurs within two hours, you should take an additional tablet.
Myth 3: Vomiting after taking the emergency contraceptive pill can not be replaced
Taking emergency contraceptive pills such as Yuketin is a familiar aftermath of the remedies, but many people do not know very well about the method of taking the wrong way to take the method, but also caused a part of the people's contraceptive failure. In our country, levonorgestrel emergency contraceptive pills, represented by Yutting, are over-the-counter and can be obtained conveniently and quickly from social pharmacies. Therefore, users must read the instruction manual or other channels to grasp the correct method of taking the pill, such as to pay attention to if vomiting occurs within 2 hours after taking the pill should be replaced and other precautions to avoid contraceptive failure. Many people mistakenly think that if the emergency contraceptive pill is taken within 72 hours, everything will be fine. In fact, due to individual differences, a small number of people after taking Yutin and other emergency contraceptive pills, there may be a slight dizziness, nausea, vomiting occurs, although the duration is very short, the incidence is also low, but if vomiting occurs within a short period of time after the drug will affect the effectiveness of the drug, it must be resolved through the timely replenishment of the same dose of the drug to solve the problem, otherwise it will increase the chances of contraceptive failure. Specifically, if vomiting occurs within 2 hours of taking the pill, the same dose should be taken immediately, and the time of the second dose remains unchanged. It is worth noting that if you eat a small amount of food while taking the pill, you can reduce or avoid nausea and vomiting.
Myth 4: The emergency contraceptive pill can replace the regular contraceptive pill
After unprotected sex, in order to avoid unwanted pregnancy, take Yutin and other emergency contraceptive pill is the best remedy, not only convenient, and contraceptive effect is more ideal. In addition, taking the emergency contraceptive pill is also an important supplement to conventional contraception, because every conventional contraception there is the possibility of failure, such as condom rupture off, short-acting contraceptive pills leakage, IUD slippage and so on, this time to take the emergency contraceptive pill is the best remedies.
But a survey shows that many women use emergency contraception in a number of irregularities, and many do not know much about how to take it. The vast majority of users are in the social pharmacy to buy their own take, a considerable number of people do not read the instructions, in the absence of a doctor's guidance, the pharmacy pharmacist has not been able to fulfill the responsibility of education, misperceptions and irregularities in the use of the case occurs. Some people mistakenly believe that taking the emergency contraceptive pill is a regular form of contraception, but it is not.
Serious adverse effects have not been reported in women who have taken levonorgestrel more than once in a menstrual cycle.
However, experts still remind the majority of women of childbearing age: emergency contraceptive pills are only an emergency remedy, not a substitute for conventional contraception, but not because of the health risks of emergency contraceptive pills to the human body, but out of the consideration of the success rate of contraception, because repeated use in a short period of time may reduce the success rate of contraception. But for women who have unprotected intercourse or whose contraceptive methods have failed, timely application of the emergency contraceptive pill is the only outlet.
Myth 6: Yutin has a strong effect on the fetus and breastfeeding women
The WHO Family Planning Service Provider Manual is a popular science book organized by the National Family Planning Commission, and in the Manual, there is a special ? Questions and Answers on Emergency Contraceptives? section. One of the questions is ? If a woman uses the emergency contraceptive pill during pregnancy, will it harm the fetus? The answer is? No, a high level of evidence has shown that emergency contraception does not cause birth defects, and if a woman is pregnant at the time of taking the pill, it will not harm the health of the fetus?
Yutin as emergency contraception special drugs, its main ingredient is levonorgestrel, is a simple progestin, the drug composition is safe, take a small dose, in the 24?48 hours after the drug can be quickly discharged from the body, will not form a negative impact on the human body. The most important thing to remember is that you should not worry about Yuktim causing a miscarriage, as progesterone and antiprogestins are very different, and only high doses of antiprogestins can cause a miscarriage.
At the same time, Yutin only contains a simple progestin, and does not contain estrogen that affects milk secretion, so? Yutin? is a suitable emergency contraceptive for breastfeeding women.
Myth 7: As long as you eat Yutin can prevent unwanted pregnancy
Since the emergency contraceptive pill as a non-prescription drugs on the market, the Shanghai Research Institute of Family Planning Clinical Research and Training Center of the safety of emergency contraceptive drugs after the market to monitor the study, which is the country's fifteenth project, the goal of this project is to explore the safety of non-prescription emergency contraceptive drugs on the market, how to prevent and reduce the drug? The goal of this project is to explore the safety of over-the-counter emergency contraceptives after they have been marketed, how to prevent and reduce the misuse and abuse of the drugs, and to provide guidance for future emergency contraceptive technology services.
This study was organized by the Shanghai Municipal Family Planning Technical Guidance Institute, in conjunction with social pharmacies, and also organized the Shanghai Municipal Surgical Monitoring Point, in addition to emergency contraception manufacturers, the establishment of a 24-hour reproductive health hotline, *** with the safety of emergency contraceptives on the market after the study. Results: 3,269 miscarriages were investigated in three hospitals in Shanghai, and of these 3,269 miscarriages, 446 cases, 13% were pregnant after using emergency contraceptive pills. This shows that the emergency contraceptive pill also has a failure rate, but more importantly, why the failure rate is higher in reality, while the failure rate in the clinical verification is only 2%.
Experts analyzing the specific situation found that the reasons for failure are concentrated in the following areas: First, 22% is the failure of the method, there are 72 hours after eating, and also taken beforehand, etc.;
Second, 78% is the use of failure, such as the use of the drug and then occurred after the occurrence of no contraceptive measures of sex, etc.;
Third, take the second piece of time exceeds the time.
The survey also asked where people got their emergency contraceptives, and nearly 98% were pharmacies. Ninety-eight percent of women said they were not instructed by a pharmacist to buy the pill. A questionnaire survey of 591 women under 19 years of age was conducted in six hospitals, three fourth-level hospitals and three maternity and child care centers. The average age of the women was a little more than 17 years old, and 21% of them had used emergency contraception; of these, only 18% had failed to use the method, and 81% had failed to use it. So the vast majority of girls pregnant is caused by the use of failure, before using the drug should be read in detail Drug instructions, in order to obtain emergency contraception in a timely manner, it is best to always have at home in case of accidents.
Myth 8: Eat the emergency contraceptive pill again can also be contraceptive
Yutin is one of the most widely used emergency contraceptive pill, but the investigation of a considerable number of people in the wrong use of Yutin, so that contraceptive errors and regret. The most common is to take Yutin as a precautionary measure, or although you know that you have to use it within 72 hours after the event, but after taking the pill and have unprotected sex. It must be pointed out that this is the wrong way to use and a misunderstanding of the emergency contraceptive pill. Emergency contraceptive pills represented by Yutin are emergency remedial contraceptive methods used to prevent unwanted pregnancy for a period of time after unprotected sex or contraceptive failure. It can be seen that Yutin is ? a post-hoc remedy? rather than a preventive method. Preventive?
This is the first time I've ever seen a condom in my life, and I've never seen a condom in my life, so I've never seen one in my life.
In addition to clear emergency contraception? Aftermath Remedy?
In addition to clarifying the characteristics of the emergency contraceptive pill, it should also be remembered that if there are many unprotected intercourse and only take Yutin once, it is also possible that the contraception fails, because in one of the previous sexual intercourse may have been pregnant. There is no point in talking about contraception when you are already pregnant.
Myth 9: Taking emergency contraception can cause acne or weight gain
Since its invention in the mid-to-late 1900s, emergency contraception, as a morning-after remedy, has made an outstanding contribution to reducing the rate of unwanted pregnancies and miscarriages in humans. Emergency contraceptive pills with levonorgestrel as an ingredient have been promoted by the World Health Organization and national family planning departments.
Yutting is the first listed emergency contraceptive pill in China, its contraceptive mechanism is: inhibit ovulation, prevent fertilization and prevent implantation, in our country has been thirteen years of history of use, on the four hundred million use of the number of times, and has achieved very good social benefits. In recent years, with the social concept of openness, Yutin as a representative of the strong demand for emergency contraceptive pills, according to the national specialized agencies of the post-marketing test, not found to have led to obesity or acne side effects.
In fact, whether from the drug mechanism or drug dosage, the view that emergency contraceptive pills have the above side effects are untenable. To two packs of Yutin, for example, each dose of 0.75mg levonorgestrel, plus progesterone stronger activity, in the human body after the absorption of 24?48 hours after the metabolism is completed after the exclusion of the body, will not reside in the body, and no matter what the role of leading to obesity and acne. The first thing you need to do is to take a look at the newest version of the pill, and you can see that it's a good idea to take a look at the newest version of the pill.
Those who think that eating emergency contraceptive pills will lead to acne or fat is a misunderstanding, strictly speaking, some half-understanding half-understanding? doctors? In August 2010, the Chinese Medical Association of Planned Parenthood held a press conference in Beijing, the famous birth control experts, researchers of the State Planning Commission, Peking University Hospital gynecologist again clarified many of the misunderstandings of Yutting and other emergency contraceptive pills. Of course, after taking the pill, a small number of people will be vomiting, nausea and other physiological reactions, some of the drug users this period will also appear in advance or lagging phenomenon, but the next month that is to return to normal, these are normal reactions.
The latest report of the World Health Organization also pointed out that: levonorgestrel-containing emergency contraceptive pills can be metabolized out of the body within 3 days after entering the human body, and there is no known health risk for repeated use, even if taken more than once in a menstrual cycle, there is no report of serious adverse effects, and there will be no long-term effects on the human body. In the case of women who are planning to get pregnant, they can do so at any subsequent sexual encounter. Myth 10: Emergency contraceptive pills work even after 72 hours
It's scary to know one thing and not know another for any serious matter. Contraception this kind of thing in the Chinese people seem to be not on the stage, but it is undeniably a very serious matter, especially for emergency contraception is more so, because a little carelessness can be? The first thing you need to do is to get a good deal of money to pay for it, and you can do that.
Yutting is the most well-known and widely used emergency contraceptive pill in China, and has been on the market for thirteen years, and a significant portion of the Chinese people already know that taking Yutting in time afterward can prevent pregnancy. However, most people don't have a correct understanding of when to take the emergency contraceptive pill, and it's the time to take the emergency contraceptive pill that's the most critical. Whether it is clinically proven or post-market testing, the conclusion is that taking Yutin within 72 hours after the event is a good way to prevent unwanted pregnancies, which has been proven by hundreds of millions of users. Within 72 hours after the incident, the sooner you take contraception, the more effective it is, this is also a **** knowledge. Because emergency contraception as a kind of aftermath remedies, in time must have urgency, if the vomiting phenomenon occurs within 2 hours after taking, need to make up for the same dose of drugs as soon as possible.
As for 72 hours after Yutin is effective or not, medical research is still in the study, some studies will increase the time frame to within 120 hours (five days), from the preliminary results of the medication did not significantly reduce the effectiveness of the drug, but its effectiveness needs to be further confirmed. However, the overall conclusion is clear: the shorter the time between unprotected intercourse and contraceptive failure, the better.
Myth 11: Human factors do not affect the efficacy of the emergency contraceptive pill
Some women grasp the time and use of Yutian, it is taken for granted that they have grasped all the true meaning of taking emergency contraceptive pills. In fact, it is not, a series of human factors can also lead to the failure of contraception, must pay enough attention.
Users of emergency contraception who suffer from colds, fever, acute enteritis and other illnesses that cause vomiting will have their medication affected. The following drugs will also have an impact on the efficacy of emergency contraception, such as penicillin antibacterial drugs, macrolides antibacterial drugs, anti-tuberculosis drugs and anti-epilepsy drugs. These drugs are commonly used in daily life, and if you don't pay attention to them, it is very easy to cause emergency contraception to fail.
In addition to the above drug interference, the following factors will also directly affect the efficacy of the drug, should cause the attention of the drug users:
1, smoking can accelerate the metabolism of emergency contraception Yutian, affecting the efficacy of the drug.
2, in the same menstrual cycle to take multiple emergency contraceptive pill contraception, will reduce the efficacy of the emergency contraceptive pill.
3, after taking the emergency contraceptive pill, before the next menstrual period, again unprotected coitus.
4, have unprotected sex several times and use emergency contraceptive pills such as Yutin only once.
5. Taking emergency contraceptive pills such as Yutin too late, beyond the optimal effective time of 72 hours.
6, the second time to take the pill more than the prescribed interval.
Myth 12: Emergency contraceptive pills have particularly large side effects
This is perhaps the biggest misconception about emergency contraceptive pills and even all contraceptives in society. The current market without a prescription can buy emergency contraceptive pills are levonorgestrel as a component, in addition to the more listed on the earliest more well-known Yutting, there are a variety of similar products.
The contraceptive mechanism of levonorgestrel emergency contraception is: inhibit ovulation; prevent sperm from combining with the egg; prevent fertilization of the egg. Some women will experience normal physiological reactions such as vomiting and nausea after taking the drug, and will recover after stopping the drug. Some women will experience an early or delayed menstrual period, which is a prominent manifestation of the contraceptive role of emergency contraceptive pills, and medically become withdrawal bleeding, and return to normal the following month.
The one-sided understanding of the side effects of the emergency contraceptive pill is mainly influenced by irresponsible reports in the media, some of which quote doctors one-sidedly, ignoring the fact that the emergency contraceptive pill is a method of emergency contraception that is supported by both the World Health Organization and the National Family Planning Commission. Of course, in today's world of white-hot commercial competition, it is often the case that certain competing industries, such as abortion providers and the condom industry, deliberately discredit the emergency contraceptive pill.
The World Health Organization's official website, which publishes the 88th issue of its 2010 Briefing Note, also specifically states that ? Accurate journalism plays an important role in disseminating information about health risks, health behaviors, and new products, while sensationalized and scary reporting can have the opposite effect. In the case of emergency contraception, there is no need to repeat the results of the many well-designed, closely-followed, multicenter studies around the world, as well as years of clinical use, that have demonstrated that levonorgestrel single-dose emergency contraception is safe and reliable. Our immediate concern is how to explain and disseminate the science in an easy-to-understand way.?
Myth 13: Multiple use of emergency contraception will lead to infertility
Some women know that emergency contraception can be used as an emergency remedy, and even have been used once or twice, but wait until the need or need to take it again, but hesitated: Emergency contraception can not be taken multiple times? If you want to have a baby in the future, will it be affected? Hesitation leads to missed opportunities to go through the pain of abortion in many people. In fact, in the National Family Planning Commission and published by the China Population Publishing House, the World Health Organization Family Planning Service Providers Manual, page 54 of the? Questions and Answers about the Emergency Contraceptive Pill? This question is answered in a sidebar. The Handbook clearly states that ECPS (levonorgestrel emergency contraceptive pills such as Yutin) is safe for multiple doses and that it has a very short duration of action. In a press conference held by the Family Planning Branch of the Chinese Medical Association in August 2010, Prof. Zheng Shurong, a researcher of the National Family Planning Commission and a gynecologist and obstetrician at Peking University Hospital, also answered this question again. The answer is that emergency contraceptives such as Yutin are safe, reversible, and can be quickly metabolized from the body, and you can get pregnant normally after stopping the pill.
From a pharmacological point of view, the dose of emergency contraceptive pills represented by Yutin is very small, a dose of only 1.5mg, in 24-48 hours can be discharged from the human body, not enough to form a negative impact on the human body, and will not affect the fertility of women in the future. And it is its rapid metabolism that ensures that ? Emergency The fact is that it is a very effective contraceptive.