1, age 18-45 years old. Male weight ≥50kg, female weight ≥45kg.
2. Citizens who meet the conditions for blood donation and are in good health.
3. You can then contact the Red Cross for registration. After reaching a certain amount, you will be informed to have a blood test, and 5ml of blood will be taken from forearm vein for HLA classification test. The test results will be stored in the data retrieval center of bone marrow bank for patients to find. Of course, you need to bring your ID card and fill out some forms to take part in the blood test. Before that, you will formally join the bone marrow bank and be ready to donate.
Health standards for voluntary donors of hematopoietic stem cells?
Alanine aminotransferase ≤25 units (hospital use ≤40 units).
Hepatitis B virus surface antigen: negative
Hepatitis C virus antibody: negative
HIV antibody: negative
Syphilis test: negative
The following is a questionnaire on the health status of voluntary blood donors.
Height: cm Weight: kg
1. Your age is between 18 and 45? Yes () No ()
/kloc-Can I donate under the age of 0/8?
There may be two reasons for limiting the age. One is because he is under the age of 18 and does not have full civil rights, so he can't complete the donation independently. The other is because of physical reasons, 18 years old is immature, and most of them can't meet the donation standard.
There are also/kloc-donations under the age of 0/8, which are all related donations and are a last resort. Therefore, this cannot be done in unrelated donations.
Upper age limit: the maximum age for registration is 45, but the age for donation is 18 ~ 55. Because successful matching may take a long time, the registration age is appropriately reduced.
2. Are you in good health? Yes () No ()
Many people have asked what is good. Without the 18 listed below, I think I am in good health.
3. Do you understand the whole process of hematopoietic stem cell donation? Yes () No ()
Those who meet the above conditions, please continue to answer the following questions:
1. Have you ever suffered from hepatitis B or hepatitis C, and are you positive for hepatitis B surface antigen or hepatitis C antibody now?
2. Do you suffer from allergic diseases, such as urticaria, bronchial asthma and drug allergy?
I have had urticaria, but I can donate it when I am cured.
Many people ask about this allergy, and I don't have an accurate answer now, but I think aspirin, penicillin, cold medicine and other common drugs should not be included.
3. Have you ever suffered from tuberculosis, such as tuberculosis, renal tuberculosis, lymphoid tuberculosis and bone tuberculosis?
4. Are there any cardiovascular diseases, such as various heart diseases, hypertension, hypotension, myocarditis and thrombophlebitis?
5. Do you suffer from respiratory diseases, such as chronic bronchitis, emphysema, bronchiectasis and pulmonary insufficiency?
6. Do you suffer from digestive or urinary diseases, such as severe gastric and duodenal ulcers, chronic gastroenteritis, acute and chronic nephritis, chronic urinary tract infection, nephrotic syndrome and chronic pancreatitis?
The diseases mentioned above refer to diseases with serious conditions that have affected their living conditions. It doesn't matter if the situation is not serious, such as common stomach problems!
7. Do you suffer from blood diseases, such as anemia, leukemia, polycythemia vera and various bleeding and coagulation diseases?
Ordinary anemia is not included. Anemia mentioned here is a serious blood disease.
8. Are you suffering from endocrine diseases or metabolic disorders, such as pituitary diseases, adrenal diseases, hyperthyroidism, acromegaly, diabetes insipidus, diabetes, etc?
9. Do you suffer from organic nervous system diseases or mental diseases, such as encephalitis, sequelae of brain trauma, epilepsy, schizophrenia, hysteria, severe neurasthenia, etc?
About brain trauma, it refers to the trauma of brain tissue. Ordinary brain abrasions do not affect donations.
10. Are there any benign tumors that affect your health?
Benign tumors that do not affect health are not included. I need to examine this concept further.
1 1. Have you ever had an operation to remove important internal organs such as stomach, kidney and spleen?
12. Do you have chronic skin diseases, especially infectious diseases, allergic and inflammatory systemic skin diseases, such as generalized eczema and systemic psoriasis? Can't have vitiligo.
13. Do you have high myopia with fundus lesions?
Many people in the consultation are highly nearsighted, so they are worried about this. In fact, fundus changes refer to fundus arteriosclerosis, retinopathy, etc., which is a relatively broad name.
Regarding this article, I specifically asked the doctor that high myopia refers to myopia above 600 degrees, but not myopia above 600 degrees can not be donated. It has a premise, fundus lesions, the specific performance is that the eyes will suddenly go blind, but will soon be better; Or feel that there are always mosquitoes flying around in front of you; Or there are some other indications, if so, you can't donate.
14. Do you have autoimmune diseases and collagen diseases, such as systemic lupus erythematosus, dermatomyositis and scleroderma?
15. Do you have sexually transmitted diseases, syphilis, leprosy, AIDS or HIV infection?
16. Have you ever taken drugs?
Marijuana, ecstasy, virus, K powder, heroin, etc. , can't eat.
17. Have you ever been refused to donate blood for free because of other diseases that can't donate blood?
18. Have you ever imported whole blood or blood components within five years?
This article refers to those who have received whole blood or blood components due to blood loss or surgery, except those who have participated in unpaid blood donation.
If one of the above items 18 is "Yes", you cannot register for warehousing.
Second, the cost problem.
During the whole process from warehousing to final donation, volunteers don't have to bear any expenses. Of course, if they want, they can donate the testing fee.
3. Why do I need my family's consent to join the hematopoietic stem cell bank?
Many friends have mentioned that I am an adult and can make my own decisions. Why do I have to ask my family's permission to register?
Imagine how excited a patient who has been waiting for a long time was when he got the news that his HLA was successfully matched with humans. Everyone longs for life, not to mention them. After getting the good news, they will step by step, check and check again, and finally enter the transplant warehouse. Their hematopoietic cells will be killed. At this time, they are the most dangerous time, waiting for the implantation of hematopoietic stem cells to save lives. If the donor at this time is due to various family members and a life, it is more painful than they don't deserve it.
Therefore, it is best to obtain the consent of the family members when entering the warehouse, so as to avoid the obstruction of the family members after the successful matching, which will not only bring greater pain to the patients, but also cause family conflicts. Of course, the consent of the family is not necessary. If the volunteers are confirmed, of course, it will not affect the donation, but it will affect their family relationship. I hope you can use your determination, your sincerity and your love to do a good job in promoting your family.
4. How many hematopoietic stem cells do donors need? Does it affect your health?
About 10g hematopoietic stem cells need to be collected.
The human body has a strong ability to regenerate hematopoietic stem cells. Under normal circumstances, all kinds of cells in the human body are constantly metabolized every day and are experiencing the cycle of aging and death. Blood loss or donation of hematopoietic stem cells can stimulate bone marrow to accelerate hematopoiesis. 1-2 weeks, all kinds of blood cells in the blood will return to the original level. So donating hematopoietic stem cells will not affect health.
5. Why use hematopoietic stem cell mobilization agent for donors before collection? Are there any side effects on human health?
Under normal physiological conditions, the number of peripheral blood stem cells is too small to meet the needs of transplantation. After drug mobilization, accelerating the generation of bone marrow hematopoietic stem cells and releasing them into peripheral blood can increase peripheral blood stem cells by 20-30 times to meet the needs of transplantation and collection. According to years of clinical observation and current international reports, drug mobilizers have no side effects on human health.
6. What methods are used in modern hematopoietic stem cell transplantation?
Modern hematopoietic stem cell transplantation adopts collecting hematopoietic stem cells from peripheral blood. A large number of hematopoietic stem cells in bone marrow blood were mobilized into peripheral blood by scientific methods, whole blood was collected from the donor's arm vein, hematopoietic stem cells were extracted by a blood cell separator, and other blood components were returned to the donor. Because the whole collection process is carried out in a closed and medically safe environment, it is extremely safe. After the collection is completed, some slight pain and discomfort will soon disappear. So far, there is no report of donor injury caused by collecting peripheral blood stem cells. Please believe that we "will not hurt another person in order to save one person".
7. Why does this "life project" hope to get support and donations from all walks of life?
This is a welfare undertaking that benefits mankind, but its operation needs a lot of money. The cost of HLA typing test for each donor is around 500 yuan. To establish a clinical database, it is very difficult to test at least hundreds of thousands of donors without the support of the whole society. Every donation you make, five yuan and ten yuan, is a support for this work. Many a mickle makes a mickle, which makes a note and ignites the hope of the patient's life. We eagerly look forward to your help.
Eight, join the China hematopoietic stem cell donor database process?
Prerequisites: age, good health, voluntary donation of hematopoietic stem cells, and understanding the whole process of hematopoietic stem cell donation.
Steps:
1. You can contact the hotlines of the Red Cross Societies around the country to register. Some places can register directly on the blood donation car, such as Beijing, Shanghai, Xi and Changsha (there are also other places, not counted).
(Please remember:
A. Seek the consent of family members, because many volunteers are strongly opposed by their families after successful matching, and they cannot complete the donation. Of course, you can insist on donating, but after all, it will have a certain impact on family relations, so try to convince your family first and explain the relevant knowledge clearly. This is also a good way of publicity. Can let more people know.
B. Bring your ID card
C, and prepare the detailed address and contact information of two different family members or relatives and friends, which are needed when filling out the form)
2. Fill in the voluntary donation form and related forms (voluntary donor consent form, voluntary donor registration form and voluntary donor health status inquiry form (two pages)), and draw 5 ml of blood.
Please pay attention to the detailed address when filling in the form, and fill in the contact information of two family members or relatives and friends, so that others can find you as soon as possible after matching you in the future.
China Hematopoietic Stem Cell Donor Database guarantees the absolute confidentiality of the personal data of hematopoietic stem cell donors, and is only used for inquiry and transplantation.
The rest of the work is left to the staff. The management center will arrange a matching laboratory to test your blood HLA typing, and input your relevant information into the network computer database of China Hematopoietic Stem Cell Donor Database, so that patients who are eager for transplantation can find a match. At this time, you will become a glorious volunteer of hematopoietic stem cell donation in China.
Only by searching for a match and further high-resolution experiments to confirm that your HLA matches the patient will you become a hematopoietic stem cell donor. This process may take months, years, or 10 years, 20 years, and even many volunteers may never have a chance to donate. Therefore, when your address and contact information change, please contact the database to update your information.
9. Process of donating hematopoietic stem cells after successful matching:
1. Patients searched in the database of hematopoietic stem cell donors in China. After the initial matching is successful, you will be informed of the physical examination with high resolution. If the high-resolution results are consistent, enter the following link; If not, you can't donate.
2. After high-resolution combination, according to the patient's schedule, enter the hospital five days before the collection date for a simple physical examination, and inject a needle of mobilization agent intravenously every day for four days (see the basic knowledge post of hematopoietic stem cells for the description of mobilization agent).
That is, he was admitted to the hospital on the 0 th day, injected with mobilization agent on the 1 ~ 4 th day and collected on the 5 th day.
3. Collection method and process: The modern hematopoietic stem cell transplantation method adopts collecting hematopoietic stem cells from peripheral blood. A large number of hematopoietic stem cells in bone marrow blood were mobilized into peripheral blood by scientific methods, whole blood was collected from the donor's arm vein, hematopoietic stem cells were extracted by a blood cell separator, and other blood components were returned to the donor. Because the whole collection process is carried out in a closed and medically safe environment, it is extremely safe. After the collection is completed, some slight pain and discomfort will soon disappear. So far, there is no report of donor injury caused by collecting peripheral blood stem cells. Please believe that we "will not hurt another person in order to save one person".
About 10g hematopoietic stem cells were collected. It contains some blood components, generally 50 ~ 100 ml. Less than blood donation. Moreover, the human body has a strong ability to regenerate hematopoietic stem cells. Under normal circumstances, all kinds of cells in the human body are constantly metabolized every day and are experiencing the cycle of aging and death. Blood loss or donation of hematopoietic stem cells can stimulate bone marrow to accelerate hematopoiesis. 1-2 weeks, all kinds of blood cells in the blood will return to the original level. So donating hematopoietic stem cells will not affect health.
X. What will happen during and after the donation, and how long will it take to work normally?
In the whole process of donating hematopoietic stem cells, a few donors may feel some discomfort, which is mainly due to the use of some drugs before donation and collection. The incidence of these reactions is very low and there is no long-term impact on donors. The collection process is longer than ordinary blood donation, similar to platelet apheresis, but it is also a kind of component blood donation.
Symptoms such as fever and muscle soreness may appear within one week after donation, and generally disappear after one week. This period of time does not affect normal work.
XI。 How to become a volunteer donor?
If you are of the right age, healthy and willing to donate hematopoietic stem cells, you can contact the Red Cross hotline to register, fill in the voluntary donation book and related forms, and draw 5 ml of blood. The management center will arrange a matching laboratory to test your blood HLA typing, and input your relevant information into the network computer database of China Hematopoietic Stem Cell Donor Database, so that patients who are eager for transplantation can find a match. At this time, you will become a glorious volunteer of hematopoietic stem cell donation in China.
Only by searching for a match and further high-resolution experiments to confirm that your HLA matches the patient will you become a hematopoietic stem cell donor. This process may be months or years, or it may be 10 years, 20 years, or even many volunteers may never have a chance to donate. So the database will always keep in touch with you.