The Carbon 13 Urea Breath Test is used to check for Helicobacter pylori infection, and is based on the principle that a stabilized nuclide 13C-labeled substrate is introduced into the body (mainly by oral administration), and that changes in the final metabolite of the substrate, 13CO?, are detected by using isotope-ratio mass spectrometry to study metabolic reactions and physiological processes in the organism.
Normal value:
The 12C/13C ratio (δ-value) was measured in the exhaled breath samples before and after the drug was taken, and it was considered to be Hp-negative if the difference between the post-expiratory δ-value minus the pre-expiratory δ-value was <4.
Abnormal result:
Determination of the 12C/13C ratio (δ value) in the breath sample before and after taking the medication, if the difference between the post-expiratory δ value minus the pre-expiratory δ value >4, then it is Hp-positive, and you are infected with Helicobacter pylori.
The need to check the crowd: Helicobacter pylori infection, peptic ulcer patients.
Extended information:
Precautions
Unsuitable for the examination of the person: no
The contraindications before the examination: the test must be carried out in the state of fasting or two hours after the meal, the patient has not taken antibiotics, bismuth preparations in the past month, Proton pump inhibitors and other Hp-sensitive drugs, otherwise it will cause false negative test results.
Contraindications for the test:
(1) Schedule the test in the morning.
(2) the test first collects the first breath sample, then take the special punch, sit quietly and wait for thirty minutes, during this time can not drink or eat anything, and then finally exhale the gas with all its strength to another collection of test tubes, the two test tubes of the collected gas will be analyzed in a specific instrument, you can get the results of the presence or absence of HP.
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