Foreword: At present, in the eyes of most people, genetic decoding is very high-end, as if only high-end people need it and it has nothing to do with them. Indeed, gene sequencing has just become known to everyone, but the role of genetic information is not yet recognized by everyone. Even many doctors do not know whether genetic information is reliable or how to use it.
In fact, gene sequencing technology has been very developed. The problem now is not the technology itself, but how to decode the sequencing results and use them in different aspects of life.
Part1: What does gene sequencing test?
Genome sequencing is to copy your genetic information from cells through a scanning instrument, then read and convert it to get your genetic sequence, and then compare it with the normal genome to see if there are any differences. Which. Usually there is a lot of differential information, and sequencing can detect it. At present, this kind of instrument is mainly produced by a company called ILLUMINA located in San Diego, USA, which is a partner of gene decoding.
The U.S. NIH launched a clinical trial (ClinSeq) a few years ago. The purpose was to explore how to further decode genes after sequencing them, and to apply the results of gene decoding to clinical methods. . Like other clinical studies, NIH recruits healthy adults and provides them with genetic information consultation before and after whole-genome sequencing to see how well they understand the results of genetic decoding after sequencing, and what impact tracking the results of genetic decoding has on their psychology and life. modalities and the impact of medical choices.
Part2: Similarities and Differences in Human Genes
The content introduced below all comes from the genetic counseling of a subject. Here, the name of the character in the Chinese movie Ziwei is used instead. actual name. The confidentiality of genetic information is an important part of Jiaxue's genetic decoding service. Because genetic information is highly private, we need to protect every participant and ensure that its genetic information is not used incorrectly.
We compare a person's genetic information to an English book. A chapter in it is a chromosome, the paragraphs in each chapter are genes, and the English letters in each paragraph are the genetic information code.
If we compare you and Ziwei, you will find that most of your paragraphs are the same. Why is that? Because you are all human. For example, the first natural paragraph of Ziwei's Chapter 3 says that she should have two legs. Your first natural paragraph of Chapter 3 should be the same as hers, because you also have two legs. But you may find that in some places, she is A and you are T. This difference is called a variant. Maybe there are only one or two different sequences in a natural paragraph, but there may be millions of different sequences in the whole book. These different sequences make you who you are and Ziwei is Ziwei. It is these different sequences that make you and Ziwei obviously different. Ziwei is characterized by gentleness, while you are generous and attractive.
Part3: What is a differential sequence
Gene decoding expresses some "variations" as "difference sequences". Most of the differential sequences are benign and do not have a critical impact on the development of the disease. These sequences of mutations simply make each of us unique. For example, Ziwei has double eyelids but you have single eyelids, Ziwei has a high nose bridge and you have a flat nose bridge, etc.
Part4: Gene decoding and disease and health
First of all, let’s briefly understand the meaning of gene decoding through a picture:
Gene decoding research shows that only a small part of The differential sequence is related to the occurrence of disease. 1. Some differential sequences can explain your health conditions
For example, high blood pressure. Gene decoding will find the causative genes of these diseases. Perhaps, such a result may be expected for you, and it is not of much use. Because even if you don't do the sequencing, you know you have high blood pressure, and other people in your family know that they are at increased risk for high blood pressure. However, genetic decoding can provide you with scientific guidance for treating high blood pressure, because genetic decoding can find that the high blood pressure in your family is different from others. Some people can prevent high blood pressure by drinking chrysanthemum tea, but you may need to use "silkworm chrysalis" pillow".
Gene decoding allows you to understand your genetic information, making your prevention of these diseases more effective and targeted.
2. Some differential sequences will provide disease risk warnings
For example, if a person carries a BRCA1/2 gene mutation, her risk of breast and ovarian cancer is much higher than that of other people. Therefore, lifestyle changes need to be made, and the strategies for early cancer screening will be different from others. The real cause can be discovered through further genetic decoding, and based on the results of genetic decoding, it can even be eradicated surgically. The same applies to other diseases, such as Alzheimer's disease, tumor risk, etc. Through genetic decoding, personalized prevention or treatment methods can be designed for you.
3. Why are the couple normal but the child is sick?
If some mutations show that the father carries a certain disease gene, but it does not cause the disease in the father, this is because he There is also a normal gene sequence in the body, which can ensure that the father is healthy and normal. However, if his wife or girlfriend also carries a disease-causing gene in this place, their children have more than a quarter chance of getting the disease. Of course, for most people, the probability of this is relatively low, and most of them are not serious diseases. But when such situations occur, they will completely destroy a family's happiness. This is the scientific basis for why Gene Decoding launches marriage and love services for everyone. That is, you may not have any symptoms yourself, but if your partner is also a carrier, your offspring are at increased risk. Such as thalassemia.
4. The mission of gene decoding
The impact of some differential sequences on our lives and health is still unclear. We don’t know whether it is benign or related to a certain disease. With the advancement of science, the mission of Gene Decoding is to maximize the navigation of everyone's healthy and happy life through continuous research, and the tool for this mission is to decode genetic information and reveal the impact of each differential sequence on human health. This makes our use of human genetic information more and more accurate, comprehensive and scientific. At the same time, we provide personalized solutions for diseases caused by changes in genetic information.
Give a chance to understand your own genes
What are your differential sequences?
When will I let you know?
Who has the right to make decisions?
Is it good for you to know? What's the downside?
How to ensure that you can understand these differential sequences?
What factors must be considered when making a decision?
These are all things you need to consider, because in the final analysis it is your genetic information, and no one needs to know yourself more than you except yourself.
?The power of knowing:
Knowing the risks of diseases will give us more time to change our lifestyles and find treatments. Perhaps the disease will be delayed or even not occur;
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Knowing the cause of the disease, we will formulate treatment plans more accurately, and perhaps we will not miss the treatment time and waste money;
Knowing it, we will remove the mental shackles, No need to live in the fear of the unknown every day!
Jiaxue Gene Medical Technology (Beijing) Co., Ltd. is a high-tech company created by a team of medical experts led by Professor Huang Jiaxue, a famous molecular biologist in my country. company.
Gene decoding upgrades genetic testing!