1. Smoking Most friends know that alcohol and aflatoxin can cause liver cancer, and smoking can cause lung cancer, but few people know that smoking is also closely related to the occurrence of liver cancer. In fact, smoking can aggravate the degree of liver fibrosis and enhance the carcinogenesis of HBV and HCV. In addition, there is a positive interaction between smoking and HBV infection. The risk of liver cancer of HBsAg positive smokers is 7 times higher than that of HBsAg positive non-smokers and 15 times higher than that of HBsAg negative non-smokers.
2. Obesity and diabetes are also closely related to the occurrence of liver cancer. Many international studies have confirmed the correlation between obesity and liver cancer. The risk of liver cancer will increase because of obesity in both men and women, and men are still slightly higher than women. This is usually related to liver damage caused by fatty liver and nonalcoholic fatty liver, and it cannot be completely repaired. Diabetes can also increase the risk of liver cancer. According to literature reports, about 25% of liver cancer in the world is caused by diabetes and obesity (body mass index >; 25).
3. Liver cancer is closely related to heredity. People with family history have a high incidence of liver cancer. Although liver cancer is not a genetic disease, it is related to heredity, and the familial nature is obvious. The risk of first-degree relatives (parents, children and sisters and brothers) with family history of liver cancer is 2.5 times that of non-first-degree relatives. The mother has liver cancer, and the incidence of liver cancer in children is significantly higher than that in fathers. Vertical transmission of hepatitis B from mother to child can significantly increase the incidence of liver cancer in their children. This phenomenon is called genetic susceptibility.
4. Hepatic fibrosis and cirrhosis are high risk factors for liver cancer. Compared with young people without cirrhosis, men with cirrhosis, old age and HBV drug resistance mutation have a significantly increased risk of liver cancer. Moreover, at least 85% of liver cancer occurs on the basis of cirrhosis, and patients with cirrhosis need to pay special attention to intrahepatic nodules, which may develop into liver cancer.
These are the problems that Dr. Yao Yao summarized for everyone, which may cause liver cancer and are easily overlooked. Let's sum up again:
The first echelon: hepatitis B, aflatoxin and alcohol
The second echelon: liver fibrosis and cirrhosis
The third echelon: smoking, obesity and diabetes
The fourth echelon: genetic factors
Finally, it should be emphasized that although there are many hepatitis B patients in China, only a few of them develop into liver cancer. While insisting on drug treatment, patients with hepatitis B must have regular physical examinations, understand and pay attention to their own situation in time, and minimize the damage caused by hepatitis B virus to the liver.
Doctor of medicine, doctor of life science, licensed pharmacist, senior nutritionist, protect life and health, reject fake health, and care for a healthy you by yourself!