According to preliminary research, this statement first came from Professor Rafer of Vermont Medical College in the United States. 1975, he measured the neurons of Alzheimer's patients by spectral analysis, and found that the aluminum content in them was 2 ~ 4 times higher than that of normal people. To this end, he believes that aluminum metal is the chief culprit leading to dementia in the elderly. At the same time, he also speculated on the pathogenic mechanism of aluminum, thinking that aluminum can combine with chemicals in neurons and hinder neurons from transmitting information, thus making people's intelligence decline and causing dementia.
We know that for all kinds of criminal cases, wise judges will attach importance to evidence, investigation and research, and will never easily draw conclusions and convict without sufficient evidence. Without sufficient experimental evidence, we can't make a simple and hasty "judgment" on whether aluminum is harmful to human health.
Now, many people agree with Professor Frey's point of view, but some people have questioned Professor Frey's point of view. They did experiments on mice, which increased the intake of aluminum ions, but the mice had no symptoms of dementia. Therefore, they oppose the theory that aluminum is the root cause of mental retardation and dementia, and think that the cause of Alzheimer's disease is complex, which is mainly related to brain atrophy.
In addition, many objective facts also challenge Professor Frey's theory. As we all know, hyperacidity can make people "heartburn" and spit sour water. At this time, doctors often ask patients to take metoclopramide (containing aluminum hydroxide) or aluminum hydroxide gel to neutralize excessive hydrochloric acid in the stomach and restore the normal function of the stomach. Obviously, this will inevitably increase aluminum ions in patients. According to Professor Frey's theory, patients with hyperacidity are prone to mental decline and even dementia. But in fact, people who often eat weishuping medicine and fried dough sticks are not worse than normal people in intelligence, and there are not many people suffering from dementia.
For another example, according to analysis and research, the aluminum content in modern human body has doubled compared with that of primitive people, but the IQ of modern people is much higher than that of primitive people. How do you explain this? As mentioned above, before 1888, metallic aluminum was very rare, and people rarely had the opportunity to touch aluminum products. It was not until 1888 that people began to be exposed to aluminum in large quantities. Does it mean that there were no dementia patients in the world before 1888? If so, what are the reasons for their dementia?
I hope chemists and medical scientists can thoroughly solve the mystery of Alzheimer's disease as soon as possible and give Al a fair explanation.