You can apply chloramphenicol eye drops on the glans. If your foreskin is a little long, turn it over frequently and rinse it with clear water. No problem!
Red papules around the glans at the coronal sulcus of penis.
It often occurs in young people and adults, generally in their twenties and forties. 10% of normal people will have it, and it is more common in young people with long foreskin and masturbation habits. It's a physiological abnormality, not an STD. It may be related to the long foreskin, more scales and chronic inflammatory stimulation.
Generally, there is no conscious symptom, and it is often found suddenly after bathing or unclean sexual intercourse, which is easy to be misdiagnosed as condyloma acuminatum.
Histopathological examination showed that pseudo condyloma was the same as vulva, with nipple-like process in appearance, slight hypertrophy of mucosal epithelium, vacuole-like performance similar to normal mucosa in the middle and upper parts of epithelium, consistent in size and shape distribution, no deep staining and contraction of nucleus, loose connective tissue around mucosa, proliferation and expansion of capillaries in connective tissue, and a little infiltration of lymphocytes.
Human papillomavirus (HPV) is negative by polymerase chain reaction, so it is not a sexually transmitted disease. It can be distinguished from condyloma acuminatum by clinical, histopathological and human papillomavirus examination, and the diagnosis is not difficult.
During the treatment, if the patient's foreskin is too long, circumcision should be done to avoid the stimulation of scales.
1. Etiology and incidence
The etiology and incidence of pearl papules on penis are still unknown. Some scholars believe that this disease belongs to an abnormal physiological development. Some scholars believe that it is related to the long foreskin. For example, Chen Xue and other surveys found that the incidence of pearl papules on the penis of young men with long foreskin was significantly higher than that of men with normal foreskin. Some scholars think that the disease may be related to infection, but Ferenczy et al. and Zhang et al. detected it in the diseased tissue, but not found it. The author observed that the patient's foreskin is too long, local sanitary conditions are poor, and the local redness and swelling caused by long-term stimulation or infection of coronal groove secretions and dirt may be the direct cause of the disease.
There are different reports on the incidence of penile pearl papules. It is reported abroad that the disease is 8.3%-30. 1% in normal male population. The investigation by Chen Fenggang and others in China found that there were 159 cases (excluding phimosis and sexually transmitted diseases) among 239 men, and the incidence rate was 66.53%. Zhang et al. found 220 cases in 9 17 cases, and the incidence rate was 24%. Chen Xue et al. found 786 cases among 2037 young men who underwent premarital physical examination, with an incidence rate of 37.92%. The author investigated 276 cases of STD clinic, and found 109 cases, the incidence rate was 39.49%. These findings indicate that penile pearl papules are common clinical diseases.
2. Clinical manifestations
Penile pearl papules are more common in men aged 20-30. The injury mainly occurs at the junction of the glans penis edge and the coronary sulcus and/or at the frenum. The lesions were papules with the size of 65438 0-3 mm, located on both sides of the frenulum. The top of the papule is round and smooth, and some papules are hairy or filamentous. Most papules do not merge with each other, and are arranged in one or more rows, which are obvious on the back of the glans and can partially or completely surround the glans. Most of the damaged colors are pearl white, a few are reddish, and some may be slightly red and swollen. There was no tenderness or ulcer, and the patient had no conscious symptoms.
3. Histopathological examination
Histopathological examination of penile pearl papules: hyperkeratosis, mild to moderate hyperplasia of epidermis, normal basal layer, slight hyperplasia and densification of dermal collagen fibers, proliferation and expansion of dermal papilla capillaries in different degrees, infiltration of a small number of lymphocytes around, and no hollow cells.
4. Key points of differential diagnosis
The main points of differential diagnosis between penile pearl papules and condyloma acuminatum are as follows: the former is confined to the edge of glans penis, with a large number of lesions, which are pearl milky white papules with smooth surface, and the lesions do not increase with the course of disease, and the acetic acid test is negative; However, the damage of the latter is not limited to the edge of the glans penis, but mostly sporadic. The damage is large, the surface is not smooth, and it is mostly cauliflower-like. With the course of the disease gradually increasing, the acetic acid test was positive. Histopathological examination showed hollow cells.
5. Principles of treatment
Penile pearl papule is a benign disease, some people can subside after a certain period of time, and some people can last for decades without change. Because the disease is not contagious and does not hinder health, there is no need for treatment. However, in order to prevent the disease from getting worse, it is very important for patients to pay attention to local cleanliness and keep a dry environment. If the patient asks for treatment, he can choose laser therapy, cryotherapy or external corrosive drugs to remove it, but remember to avoid scar caused by excessive injury and cause the patient's pain. For some patients, these lesions may recur after resection.