Recently, according to foreign media reports, researchers at the University of Leeds pointed out that people who are overweight but appear to be metabolically healthy may have a particularly good blood supply to their fat cells.
In reality, there are some obese people whose metabolism is normal. Although this is amazing and a fact that has puzzled scientists for many years, this new study may reveal the reasons.
In this study, the researchers studied a receptor called IGF 1-R, which plays a role in the growth of new blood vessels. The research team removed the receptors of vascular wall cells in mice fed with high-fat diet and found that new blood vessels grew into fat.
Surprisingly, in the long run, this actually leads to the protection of heart and circulatory diseases.
Although the reason is not clear, researchers believe that blood vessels in fat may release bioactive chemicals, prompting fat cells to turn brown. Brown fat burns calories to generate heat, which helps to control blood sugar, blood pressure and cholesterol levels.
Researchers now hope to use these findings to help develop drugs that can replicate this process and prevent heart disease, but at present, it is necessary to determine the healthy biological activity signals released by blood vessels in order to fight obesity-related heart and circulatory diseases.
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