The commonly used drugs are antihistamines, which are classified as H 1 receptor antagonists. At present, ketotifen, clomastine, cetirizine, levocetirizine, olopatadine, fexofenadine, ebastine and epinadine are commonly used. H2 receptor antagonist, usually cimetidine. Doxepin can antagonize both H 1 and H2 receptors, and is also commonly used for chronic urticaria. Glucocorticoid can control the symptoms of the disease, but it can not affect the basic process of the disease, and it is easy to relapse after stopping taking the drug. Therefore, glucocorticoid should not be used as the first choice and basic drug for the treatment of urticaria, especially when other drugs can not control the condition of chronic urticaria, and should be reduced and stopped gradually after control.
For chronic urticaria, a receptor antagonist of H 1 is usually selected first. If the curative effect is not good, another drug of H 1 is added, and two different types of combined treatment are adopted. If this therapy still can't control the disease, you can choose H 1 combined with H2 antagonist, or you can use doxepin plus H 1 receptor, and observe for more than 3 ~ 5 days each time. At present, it is considered that the combination of H 1 and H2 antagonist is effective. It is recommended to use drowsy drugs during the day and sedative drugs at night, as well as transfer factors and vitamins. Traditional Chinese medicine has a good effect on chronic urticaria, such as Yupingfeng Granule.