What is cloning technology? How to apply it to biomedicine and agriculture?

Cloning technology refers to the reproduction of an organism that is exactly the same as the original individual through asexual reproduction. At the cellular level, cloning technology can be realized by somatic cell nuclear transfer, that is, the nucleus of a mature cell is transplanted into another enucleated egg cell, so that it can develop into a new individual.

In the biomedical field, cloning technology is used to study cell proliferation, tissue/organ regeneration and human diseases. For example, cloning technology can be used to copy a large number of genes or cells with specific functions, test their pharmacodynamics and toxicology, and make disease models. At the same time, cloning can also be used to treat some genetic diseases. The specific method is to extract the nuclei of some damaged cells in patients' tissues, then implant them into healthy eggs and transplant the synthesized early embryos (or stem cells) back into patients. In fact, cloning technology is widely used in creating transgenic animals and plants, producing antibodies and studying stem cells.

In agriculture, cloning technology is used to create efficient, robust and better quality livestock, poultry and crop varieties. Animals or plants with the same genetic qualities can be bred by nuclear transfer, and these qualities can be stably inherited in future generations. For example, in cattle, sheep and other domestic animals, scientists have successfully extracted and copied the genes of high-yield dairy cows such as Einstein from fertilized eggs/embryos through cloning technology, and injected them into the eggs of healthy dairy cows, so that their offspring can also have the same amount of milk. In addition, in terms of crops, cloning technology can also be used to enhance the resistance of plants to disasters, pests and diseases, promote crop growth and increase yield.