Since the daily intake of nickel is 70 ~ 260μ g/d, the possible requirement of human body is 25 ~ 35μ g/d according to the results of animal experiments. ..
Overexpression
Intake of 250 mg of soluble nickel every day can cause poisoning. Some people are sensitive and will be poisoned if they ingest 600 μ g. According to animal experiments, chronic excessive intake or exposure can lead to the degeneration of myocardium, brain, lung, liver and kidney.
Nickel deficiency
Animal experiments show that the lack of nickel will lead to slow growth and decreased fertility. ?
chrome
I. Invasive route of health hazards: inhalation and intake.
Health hazards: Metal chromium has almost no harmful effects on human body, and there are no reports of industrial poisoning. Chromium entering human body accumulates, metabolizes and clears slowly in human tissues. After entering the blood, chromium mainly combines with ferroglobulin, albumin and r- globulin in plasma. Hexavalent chromium can also penetrate the erythrocyte membrane. Within 15 minutes, 50% of hexavalent chromium can enter cells and then combine with hemoglobin. Metabolites of chromium are mainly excreted from kidneys, and a small amount is excreted through feces. Hexavalent chromium is mainly chronic toxicity to human beings. It can invade human body through digestive tract, respiratory tract, skin and mucous membrane, and mainly accumulate in liver, kidney and endocrine glands in the body. Those that enter through the respiratory tract are easy to accumulate in the lungs. Hexavalent chromium has strong oxidation, so chronic poisoning often starts from local damage and gradually develops to incorrigible. When it invades the human body through the respiratory tract, it begins to invade the upper respiratory tract, causing rhinitis, pharyngitis, laryngitis and bronchitis.
Second, toxicological data and environmental behavior.
The water polluted by hexavalent chromium is usually yellow, and the degree of water pollution can be preliminarily judged according to the different shades of yellow. When yellow appears, the concentration of hexavalent chromium is 2.5 ~ 3.0 mg/L.
Carcinogenicity determination: animals are suspicious.
Hazard characteristics: Its powder can burn under high temperature and open flame.
Combustion (decomposition) products: Natural decomposition products are unknown.
Basically harmless. This is a coin