Can arthritis be treated with stem cells?

Mesenchymal stem cells (MSCs) have always been regarded as seed cells with broad application prospects in the fields of tissue engineering and regenerative medicine, and they are pluripotent adult stem cells. Studies have shown that mesenchymal stem cells can be induced to differentiate into osteoblasts, adipocytes, muscle cells, nerve cells and epithelial cells in vitro. Many in vivo studies have shown that mesenchymal stem cells can migrate to the injured site and participate in the repair of damaged tissues.

Japan's research on repairing tissue defects with stem cells has achieved fruitful results. At present, some scholars adopt the culture of chondrocytes and mesenchymal stem cells, which is not only conducive to the microenvironment of mature chondrocytes, but also conducive to the secretion of cytokines to induce mesenchymal stem cells to differentiate into chondrocytes. At the same time, cytokines secreted by mesenchymal stem cells promote cell proliferation and matrix synthesis, and prevent chondrocytes from dedifferentiating in vitro.

Intervention of stem cells in arthritis solution

Option one? Directional venous reinfusion of stem cells

Stem cell reinfusion therapy is to extract high-quantity and high-quality stem cells and reinfusion them to patients. Use the self-replication and differentiation potential of stem cells to repair damaged cells and restore the normal function of damaged organs and tissues.

Using the automatic homing function of stem cells, that is, stem cells will automatically transfer to the damaged lesions in the human body and differentiate into various cells needed, so as to repair the inherent cells of the human system, restore the system function, improve the symptoms of patients and achieve the purpose of treatment.

Scheme 2: Local targeted transplantation of stem cells.

Stem cell targeted transplantation is to transplant a large number of high-quality stem cells directly into the joint cavity of patients, and use the self-replication and differentiation potential of stem cells to repair damaged cells and restore the normal function of damaged organs and tissues.

Stem cells will reach the focus to repair and replace damaged cells and tissues, differentiate into immune cells to treat and repair the immune system, and restore the immune regulation function to normal level; On the other hand, stem cells secrete a variety of cytokines, which can inhibit inflammatory cell mediators and reduce bone and joint,

Synovial destruction can effectively control the progress of the disease, so as to achieve the purpose of effective treatment of the disease.

With the maturity of stem cell technology in Japan, more and more clinical cases have caused some domestic osteoarthritis patients to go to Japan for stem cell therapy through animal husbandry. As a new treatment method, stem cell therapy will eventually become the third generation of disease treatment after drug therapy and surgical treatment.