(2) The application of sudorific agents, nerve center stimulants.
①Maximilian is a central nervous system stimulant, and it has antagonistic effect on barbiturates, guiding sleep energy, chloral hydrate, valium and other drugs, and the common dosage is 50mg added to 5% dextrose for intravenous drip, and the static speed should not be too fast in order to prevent convulsions, and repeat the administration of the drug according to the condition as appropriate.
②Indian defense has toxin: a strong central nervous system stimulant, the medulla oblongata, the midbrain has an excitatory effect, is an antagonist of barbiturate poisoning, 1 ~ 3mg of patients with severe disease, every 20 minutes intramuscular or intravenous injection, until the corneal reflexes or tendon reflexes until the emergence of the attention to prevent the occurrence of convulsions in excess of the drug can be given alternately with the serotonin, to reduce the side effects.
③Niclosamide: is a selective medullary respiratory center stimulant, can be used in central respiratory failure.
(3) Symptomatic treatment and care:
①Establishment of intravenous access is one of the important measures for timely resuscitation, to ensure the accurate implementation of the medical advice, intravenous drug administration, can replenish fluids, electrolytes, to correct shock and electrolyte disorders, acid-base imbalance of the rational use of antimicrobial agents, prevention and control of infection.
②Keep the airway open and oxygen therapy: to be oxygen inhalation, improve the hypoxia caused by respiratory distress and correct cyanosis, tracheal intubation or tracheotomy if necessary, ventilator-assisted respiration, comatose patients should take the head in a lateral position, to prevent the tongue from falling back, and suctioning the mouth in a timely manner, to keep the airway open, and regular monitoring of the blood gas analysis, and timely correction of hypoxemia.
③Closely observe the change of condition and do a good job of basic care. The focus of treatment and care is to maintain respiratory, circulatory, renal function, and prevent secondary infection. Comatose patients according to the coma routine care, observe the changes of vital signs, and detailed records, found abnormal performance, timely cooperation with the doctor to deal with, such as temperature rise, may suggest secondary infection, respiratory rhythm, frequency changes, may suggest that the intoxication after cerebral edema or electrolyte disorders, acid-base imbalance; heart rate and blood pressure changes, suggesting that the effective circulatory capacity or cardiac function abnormalities, etc.. Strengthening basic nursing care is especially important for patients in coma and respiratory and circulatory failure. Comatose people can not eat through the mouth and lose the ability of oral self-cleaning, therefore, keeping the airway open and doing good oral care can reduce complications. At the same time, skin care should also be done to prevent the occurrence of decubitus ulcers, so as not to add to the patient's pain. For coma, convulsions patients should pay attention to protection, to prevent falling out of bed. Where comatose patients put indwelling urinary catheter, to facilitate the discharge of toxic substances, but also timely observation of urine properties and urine volume, and accurately be recorded for the benefit of medical staff to understand the patient's access. If there is oliguria, urinary closure and yellow bile, hepatomegaly and other liver and kidney function impaired performance, timely blood tests of liver and kidney function. The consciousness of the gradual recovery of the poisoned patient, we should target to do a good job of ideological work, give guidance on the use of medication, encourage the patient to stimulate the courage to survive and recover as soon as possible confidence, and at the same time do a good job of family members, in order to cooperate with the resuscitation period and the recovery period of the smooth progress of the medical care, and strive to obtain a satisfactory therapeutic effect.
(4) The condition of the medical unit, the serious poisoning of blood purification or dialysis treatment, should be strictly aseptic technical operation, pay attention to the protection of isolation, to prevent the occurrence of nosocomial infection.