Urticaria is commonly known as rash. It is a localized edema reaction caused by the expansion and permeability increase of small blood vessels in skin and mucosa, which often occurs repeatedly. It is scientifically proved that the IgE immunoglobulin in the immune system of patients with urticaria is 1- 10 times higher than that of normal people. These higher IgE will disturb the human immune system and make it sensitive, which will lead to urticaria. Kangminyuan probiotics can effectively inhibit the abnormality of IgE immunoglobulin, reduce allergen-induced IgE production, and finally play a role in preventing and treating urticaria.
Why does urticaria always break out at night? This is the most incomprehensible problem for many patients with urticaria. Patients have encountered such a problem in the process of suffering from urticaria, that is, during the day, the pain and itching in the affected area of urticaria are not so serious, but at night, they feel the pain and itching in the affected area of urticaria. Why?
First, the cause of urticaria is aggravated at night:
1, the hormone secretion is the most in the morning, but relatively less at night, and its function of inhibiting the release of allergic mediators is weakened, so urticaria is often serious at night.
2. People are often in a state of vagus nerve excitation and sympathetic nerve inhibition during sleep, while vagus nerve is dominant and acts on bronchial smooth muscle. Increased vagal excitability will cause contraction of bronchial smooth muscle, which will lead to spasm of bronchial smooth muscle, airway stenosis and dyspnea.
3. Affected by inhalation allergy factors at night. Patients' pillows and quilts are often filled with animal fur and other impurities, and the particles they carry are often the factors that cause allergies.
4, urticaria itching at night is mainly due to the weakening of human function at night, slow blood flow, lack of nutrition in the skin, so the itching at night is heavier.
5. At night, people are not very active, not too disturbed by the outside world, sensitive to their own changes and itchy.
6. The temperature is low at night, and the air with temperature is inhaled into the respiratory tract, which leads to the disorder of the relaxation and contraction function of bronchial smooth muscle and aggravates asthma.
7. When people sleep at night, the mechanical sensory function of the chest is weakened and the airway secretions are not discharged smoothly. Blocking or stimulating the airway can cause wheezing attacks. After sleep, the airway is in a natural or fatigue state, and sputum deposits, blocking the airway and causing laryngeal obstruction.
Second, the diagnosis of urticaria:
Urticaria is easy to diagnose, but it is difficult to determine the cause. General and frequent examinations: asking about medical history, detecting antinuclear antibody and IgE antibody, and the increase of IgE antibody is very helpful for the diagnosis of urticaria.
Third, the treatment of urticaria:
1. Oral antihistamines, such as loratadine and chlorphenamine cyproheptadine, can compete with histamine in vivo, thus effectively relieving skin allergic symptoms. But antihistamines can't inhibit the production of histamine, so they can't prevent urticaria from recurring. Moreover, histamine products have the function of inhibiting nerves, and are prone to dizziness, drowsiness and other adverse reactions after taking them, and long-term use will cause great damage to liver and kidney.
Traditional Chinese medicine treatment: some traditional Chinese medicines with heat-clearing and detoxification effects are often used for treatment. Although it can clear away dampness and heat in the body, dredge the circulation channels in the body, and achieve the improvement of detoxification and purging fire, it does not change the root cause of urticaria, so it cannot prevent its recurrence.
3. New concept of urticaria treatment: Eczema is treated with formula food with special medical use of microorganism Kangminyuan probiotics. Intestinal flora imbalance is a major feature of children with eczema. Because anti-allergic probiotics can increase the diversity of intestinal flora, regulate the activation of TH cytokines, inhibit TH2-type response, enhance TH 1 type immune response, up-regulate immune cells, and accelerate the repair of skin and mucosal barrier function.
IgE antibody immunomodulator (Kangminyuan anti-allergic probiotics) Urticaria mostly belongs to type I allergic diseases (also known as IgE-mediated allergic reactions), and the causes are complex. Generally, it will change from acute urticaria to chronic urticaria, which will recur for a long time, but it will not heal after long-term treatment. At present, people only pay attention to the treatment of urticaria, but not to the allergic reaction itself: the stimulation of allergens leads to the disorder of human immune function and the abnormal increase of immunoglobulin E in the body. Repeated contact with allergens leads to a large number of IgE antibodies in the body and attached to immune cells for a long time, which leads to the secretion of inflammatory mediators such as histamine and harms itself. From the immunological point of view of urticaria, the fundamental treatment should be to control IgE. At present, the treatment of urticaria mostly stays in the inflammatory stage such as antihistamine, and some people will try to treat it by improving immunity, but allergy is not caused by low immunity, and the imbalance of five immunoglobulin secretion in human body is the fundamental cause of the disease. At present, the treatment method of IgE anti-human antibody to solve urticaria in international immunology research is to supplement anti-allergic probiotics Kangmin source to reduce IgE antibody in human body, and adjust immunoglobulin balance by stimulating interferon secretion, thus restoring human immune response.