Generally speaking, sertraline can help, but if not, it should be used under the guidance of a doctor. Premature ejaculation refers to the sexual disharmony disorder after the penis is inserted into the vagina, when the female has not reached orgasm and the male has less than 2 minutes of sexual intercourse. Generally, 30% of men have this situation. Although the problem is small, it makes the quality of sexual life not high, and may also cause sexual dysfunction such as impotence, with serious consequences, which should be paid attention to and treated as soon as possible. It is generally believed that premature ejaculation refers to the phenomenon that men ejaculate after penis erection, before entering vagina, or when they are properly incorporated. When they just enter but have not twitched, the penis naturally weakens and enters refractory period. Clinically, premature ejaculation is diagnosed when penile erection does not enter the vagina. Those who can enter vaginal intercourse ejaculate quickly without moving a few times are also defined as premature ejaculation.